Artemis Comparison Tool (ACT)

Artemis Comparison Tool (ACT)

Artemis Comparison Tool (ACT)

Overview

ACT is a Java application for displaying pairwise comparisons between two or more DNA sequences. It can be used to identify and analyse regions of similarity and difference between genomes and to explore conservation of synteny, in the context of the entire sequences and their annotation. It can read complete EMBL, GENBANK and GFF entries or sequences in FASTA or raw format.

Related Software

Two separate ACT-related web applications have been developed.

  • WebACT was developed at Imperial College, and allows users to generate comparisons from their sequence files or use a set of pre-computed comparisons. All comparison files can be downloaded for local use or launched in ACT.
  • DoubleACT was developed by Anthony Underwood and Jonathan Green at the Public Public Health England and allows you to paste or upload sequences to generate ACT comparison files.

Download and Installation

Please see our GitHub page for download and installation instructions.

Learn and Support

For more information and advice on using this software please see the ACT manual and our GitHub page.

In addition, an email discussion list called artemis-users is available and posts to the list since September 2001 are archived at mail-archive.com

License and Citation

ACT is available under GPL3.

If you make use of this software in your research, please cite as:

ACT: the Artemis Comparison Tool.

Carver TJ, Rutherford KM, Berriman M, Rajandream MA, Barrell BG and Parkhill

Bioinformatics (Oxford, England) 2005;21;16;3422-3
PUBMED: 15976072; DOI: 10.1093/bioinformatics/bti553

Contact

If you need help or have any queries, please contact us using the details below.

Our normal office hours are 8:30-17:00 (GMT) Monday to Friday.

Related Programmes

Publications

  • ACT: the Artemis Comparison Tool.

    Carver TJ, Rutherford KM, Berriman M, Rajandream MA, Barrell BG and Parkhill J

    Bioinformatics (Oxford, England) 2005;21;16;3422-3

  • WebACT: an online genome comparison suite.

    Abbott JC, Aanensen DM and Bentley SD

    Methods in molecular biology (Clifton, N.J.) 2007;395;57-74