
Dr Salman Tamaddon-Jahromi
Technical Specialist
Salman specialises in the application of iPSC-derived neuronal models and advanced CRISPR-Cas9 techniques to generate scientifically rigorous experimental evidence for the validation or invalidation of identified targets from genome-wide CRISPR-Cas9 screens.
By collaborating closely with academic and industrial partners, he has successfully established a customised framework for large-scale systematic target validation. This framework encompasses the establishment of orthogonal complementary workflows, implementation of quality and performance controls, and development of disease-relevant phenotypic assays related to autophagy & lysosomal dysfunction, protein aggregation, and synaptic homeostasis disruption.