My work focuses on patients with autoimmune disease, primarily those with systemic lupus erythematosus (SLE). I’m interested in exploring how gene expression in these patients is influenced by genetics and how this may be altered in patients with varying disease presentation and different treatment responses. By recruiting cohorts with patients from across multiple ancestry backgrounds, we also hope to more accurately represent the populations affected by SLE and investigate how genetic ancestry may impact disease.
I completed my PhD at the University of Edinburgh where I was supervised by Dr Graeme Cowan. My work focused on the sequencing of adaptive immune receptor (BCR and TCR) repertoires in rheumatoid arthritis and other immune conditions. In particular, I was interested in linking receptor characteristics with cell phenotype and understanding how repertoire sequencing may inform treatment decisions.
My timeline
Senior Staff Scientist at the Sanger Institute
Started as a Postdoctoral Fellow at the Sanger Institute
Submitted PhD thesis - Understanding adaptive immunity using immune receptor repertoire sequencing
Joined the Wellcome Trust Hosts, Pathogens and Global Health 4 Year PhD Programme, University of Edinburgh (supervised by Graeme Cowan)
Began MSc in Integrated Immunology, University of Oxford