Professor Sir Mike Stratton, FMedSci FRS

Senior Group Leader

Mike Stratton is a Senior Group Leader in the Cancer, Ageing and Somatic Mutation Programme. His primary research interests have been in the genetics of cancer. His early research focused on inherited susceptibility. Mike mapped and identified the major high-risk breast cancer susceptibility gene BRCA2 and subsequently a series of moderate-risk breast cancer and other cancer susceptibility genes.

In 2000 Mike initiated the Cancer Genome Project at the Wellcome Sanger Institute which conducts systematic genome-wide searches for somatic mutations in human cancer. Through these studies he discovered somatic mutations of the BRAF gene in malignant melanoma and several other mutated cancer genes in lung, renal, breast and other cancers. He has described the basic patterns of somatic mutation in cancer genomes revealing underlying DNA mutational and repair processes.

Mike is a Fellow of the Royal Society (FRS) and was Knighted by the Queen in 2013.

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