Dr Laura Riva

Principal Bioinformatician

Laura is currently studying mutational signatures of cancer development in mice which have been exposed to known or suspected carcinogens.

My main aim is to use and develop computational approaches to analyse and interpret cancer genomes. I am interested in identifying somatic mutations, driver genes and in understanding the biological mechanisms underlying mutational processes. 

I have previously implemented computational methods to identify cancer driver genes and putative cancer predisposing genes. In addition, I have contributed to the identification of genes essential for tumour growth by using in vivo genetic screens of patient-derived tumours. As a postdoctoral fellow, I developed systems biology approaches to integrate -omics data to identify active pathways and to study regulatory networks in neurodegenerative disorders.
 

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