PhD Student in Computational Biology - Focus on somatic mutations in pre-malignant lung disease and accelerated ageing phenotypes.
I am a 2nd year PhD student jointly supervised by Inigo Martincorena and Peter Campbell, particularly interested in understanding the mechanisms underlying early cancer evolution and prevention. In particular, I am specializing in computational analysis of genomic data from high-throughput sequencing, with the goal to advance my understanding about the earliest steps of tumourigenesis occuring in healthy individuals. In line with this, I am working on the characterisation of the landscape of somatic variation in the proximal and distal airway of lungs from individuals with previous smoking histories. In addition, I am interested in the contribution of somatic variation to ageing, exploring the routes and features of accelerated ageing phenotypes (progeroid syndromes). I am curious to learn about entrepreneurship in biotechnology and health, including but not limited to key strategic, technical, financial and commercial issues linked to the creation and development of an idea into a start-up.
Feel free to get in touch – happy to discuss anytime đ
My timeline
Science & Management (MBA) Fellow - CollÚge des Ingénieurs
PhD Student - Dr. Inigo Martincorena, Dr. Peter Campbell - Cancer, Ageing and Somatic Mutations - Wellcome Sanger Institute
Visiting Student - Prof. Dr. C. Curtis, Dr. K. Karlsson - Cancer Computational and Systems Biology Group - Stanford University
Graduate Research Student - Prof. Dr. O. Stegle, Dr. N. Casiraghi, Dr. H. Susak - Statistical Genomics and Systems Genetics - DKFZ German Cancer Research Center
Visiting Student - Prof. Dr. C. Swanton, Dr. S. Turajlic - Cancer Evolution and Genome Instability Laboratory - The Francis Crick Institute
Master of Science - University of Heidelberg
Graduate Student Research Assistant - Prof. Dr. M. v. Knebel-Doeberitz, PD Dr. M. Kloor - Department of Applied Tumor Biology - University Hospital Heidelberg
Bachelor of Science - University of Heidelberg
Connect with me on Twitter
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Amazing to be at #EACR2022 in person! Beautiful city & exciting science ahead. Very happy to represent the @imartincorena and Campbell groups @sangerinstitute together with superâïž @_Luke_MRH_. If you are around, would be fantastic to see you join for our talks on Wednesday đ„°
Delighted to share our latest work in its final form (and open access!). Here, we studied the rate at which somatic mutations accumulate in different species to address some long-standing hypotheses. đ§”⊠1/
https://www.nature.com/articles/s41586-022-04618-z
Incredibly excited to share our paper âSomatic mutation rates scale with lifespan across mammalsâ now published @nature.
https://www.nature.com/articles/s41586-022-04618-z
An illustrated & updated tweetorial⊠[1/24]
