
Lucy Holland
Higher Laboratory Scientist Apprentice
I am a Higher Laboratory Scientist Apprentice based within Cellular Generation and Phenotyping. As the group’s first apprentice, my time is divided between laboratory work and studying towards a BSc degree in Applied Biosciences. My specialisms include aseptic cell culture (iPSCs, neuronal networks, and cancer organoid models), high-throughput protein screening, and immunocytochemistry techniques for imaging.
Presently, I am part of ProjectGro which aims to derive and generate a useful biobank of physiologically relevant in vitro organoid models for the cancer research community. This involves organoid culture and performing quality control processes.
Previously, I was part of the iNeurons project which aimed to map functional interactions between human glial and neuronal cells at scale. This involved developing a high-throughput screen for human glial proteins that induce synapse formation and functional maturation of human cortical neurons. Against this project backdrop, I received training in culture and differentiation of induced pluripotent stem cells, culturing neuronal networks, protein screening, and immunofluorescence staining for imaging.
My timeline
Joined ProjectGro in CGaP culturing cancer organoid models and performing quality control processes.
Joined the iNeurons project in CGaP culturing and differentiating induced pluripotent stem cells & neuronal networks, screening proteins, and cell imaging using immunofluorescence staining.
Trained in CGaP’s Media Team, learning fundamental cell culture and laboratory techniques.
Joined as a Higher Laboratory Scientist Apprentice in the Cellular Generation and Phenotyping Group (CGaP), Wellcome Sanger Institute
CertHE Natural Sciences - Open University