Charlotte is a PhD student co-supervised by Sarah Teichmann and Sam Behjati. Her research is part of the Human Cell Atlas and aims to establish a developmental map of B cells in early embryology. She is interested in looking at B cells lineage and in studying the transcriptional dynamics underlying different types of B-cell related childhood cancers.
Prior to her PhD, Charlotte pursued her undergraduate degree at the University of Cambridge with a focus on developmental biology and neuroscience. During her studies, she had the opportunity to work in Prof. Ozanne’s lab where she looked at developmental programming of metabolic pathways in embryology. For her undergraduate thesis, Charlotte developed a computational tool to track the activity of IPSC-derived cortical neural networks as they develop in vitro (Dr Hugh Robinson).
Charlotte’s rotation in Sarah Teichmann’s lab focused on maternal/fetal immune interactions, leading to a new found interest in single cell technologies and immunology. Charlotte’s current research on the transcriptional regulation of early embryonic B cells lies at the interface of developmental biology and cancer immunology.
Programmes and Facilities
Cancer, Ageing and Somatic Mutation
The Cancer, Ageing and Somatic Mutation Programme seeks to provide leadership in data aggregation and informatics innovation, developing high-throughput cellular models ...