Dr Linda Grillova

Carrier Development Fellow

I am a molecular biologist and microbiologist focusing on genomics, transcriptomics, and molecular epidemiology of pathogenic spirochetes. 

The ultimate goal of my current focus is to take advantage of the recently described in vitro co-culture model of Treponema pallidum and link its use to high throughput genomic approaches to provide unique insights into the gene expression profiles of this pathogen. We aim to generate novel fundamental data which can lead to identification of functional pathways and prediction of the function for hypothetical genes, give light to the patterns of selection we see in genomic data and a better understanding of the key growth dependencies that could inform future axenic cultivation of Treponema pallidum. With a better understanding of basic biology we hope to introduce a more mechanistic understanding to surveillance and genomic epidemiology of syphilis.

My timeline

• Career Development Fellow (BBSRC Discovery Fellowship), Parasites and Microbes Programme, Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridgeshire, UK.

• Postdoctoral Fellow (Marie Skłodowska-Curie Action), Parasites and Microbes Programme, Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridgeshire, UK.

• Postdoctoral Fellow, Biology of Spirochetes, Department of Microbiology, Institut Pasteur, Paris, France.

• Postdoctoral Fellow, Bacterial Genetics and Genomics research group, Faculty of Medicine, Masaryk University, Czech Republic.

• PhD Fellow, Institute of Forensic Medicine, University of Zurich, Zurich, Switzerland.

• PhD Fellow, Medical Biology at Faculty of Medicine, Masaryk University, Czech Republic.