Sofia Chen

PhD Student


This person is a member of Sanger Institute Alumni.

My research focuses on melanoma genetics and immuno-oncology.

My first project involves profiling the genetic landscape of a large number of human primary melanoma tumours, identifying novel driver genes and interactions. My second project uses genome-wide CRISPR-Cas9 screening to understand how tumour PD-L1 expression can be downregulated to reverse immune cell exhaustion and facilitate tumour cell killing.

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