Dr Ellen Bushell

Senior Staff Scientist


This person is a member of Sanger Institute Alumni.

Working with Oliver Billker and Julian Rayner, I am the project manager for PlasmoGEM (http://plasmogem.sanger.ac.uk/), a Wellcome Trust Sanger Institute based project that generates and freely distributes tools for the genetic manipulation of the Plasmodium malaria parasites.

My primary research interest is the development of scable experimental genetic tools for the manipulation of the rodent malaria parasite Plasmodium berghei. My focus is on tools that allow for high-throughput screening of multiple genes in parallel, in loss-of-function as well as gain-of-function in vivo assays. I am particularly interested in using data from such assays to gain novel insight into mechanisms underpinning parasite pathogensis, metabolism and drug resistance.

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