Dr Charles Andrew Steward | Former Senior Computer Biologist

This person is a member of Sanger Institute Alumni.

Steward, Charles Andrew

Dr Charles Steward left the Sanger Institute in June 2016, this page is being maintained as record of his work at the Institute.


  • Ptpn22 and Cd2 Variations Are Associated with Altered Protein Expression and Susceptibility to Type 1 Diabetes in Nonobese Diabetic Mice.

    Fraser HI, Howlett S, Clark J, Rainbow DB, Stanford SM et al.

    Journal of immunology (Baltimore, Md. : 1950) 2015;195;10;4841-52

  • Identification of the inflammasome Nlrp1b as the candidate gene conferring diabetes risk at the Idd4.1 locus in the nonobese diabetic mouse.

    Motta VN, Markle JG, Gulban O, Mortin-Toth S, Liao KC et al.

    Journal of immunology (Baltimore, Md. : 1950) 2015;194;12;5663-73

  • Characterization of an Additional Splice Acceptor Site Introduced into CYP4B1 in Hominoidae during Evolution.

    Schmidt EM, Wiek C, Parkinson OT, Roellecke K, Freund M et al.

    PloS one 2015;10;9;e0137110

  • The Vertebrate Genome Annotation browser 10 years on.

    Harrow JL, Steward CA, Frankish A, Gilbert JG, Gonzalez JM et al.

    Nucleic acids research 2014;42;Database issue;D771-9

  • Current status and new features of the Consensus Coding Sequence database.

    Farrell CM, O'Leary NA, Harte RA, Loveland JE, Wilming LG et al.

    Nucleic acids research 2014;42;Database issue;D865-72

  • Fine mapping of type 1 diabetes regions Idd9.1 and Idd9.2 reveals genetic complexity.

    Hamilton-Williams EE, Rainbow DB, Cheung J, Christensen M, Lyons PA et al.

    Mammalian genome : official journal of the International Mammalian Genome Society 2013;24;9-10;358-75

  • Structural and functional annotation of the porcine immunome.

    Dawson HD, Loveland JE, Pascal G, Gilbert JG, Uenishi H et al.

    BMC genomics 2013;14;332

  • The non-obese diabetic mouse sequence, annotation and variation resource: an aid for investigating type 1 diabetes.

    Steward CA, Gonzalez JM, Trevanion S, Sheppard D, Kerry G et al.

    Database : the journal of biological databases and curation 2013;2013;bat032

  • The B10 Idd9.3 locus mediates accumulation of functionally superior CD137(+) regulatory T cells in the nonobese diabetic type 1 diabetes model.

    Kachapati K, Adams DE, Wu Y, Steward CA, Rainbow DB et al.

    Journal of immunology (Baltimore, Md. : 1950) 2012;189;10;5001-15

  • An integrated encyclopedia of DNA elements in the human genome.

    ENCODE Project Consortium

    Nature 2012;489;7414;57-74

  • GENCODE: the reference human genome annotation for The ENCODE Project.

    Harrow J, Frankish A, Gonzalez JM, Tapanari E, Diekhans M et al.

    Genome research 2012;22;9;1760-74

  • Mouse genomic variation and its effect on phenotypes and gene regulation.

    Keane TM, Goodstadt L, Danecek P, White MA, Wong K et al.

    Nature 2011;477;7364;289-94

  • Evidence that Cd101 is an autoimmune diabetes gene in nonobese diabetic mice.

    Rainbow DB, Moule C, Fraser HI, Clark J, Howlett SK et al.

    Journal of immunology (Baltimore, Md. : 1950) 2011;187;1;325-36

  • Nonobese diabetic congenic strain analysis of autoimmune diabetes reveals genetic complexity of the Idd18 locus and identifies Vav3 as a candidate gene.

    Fraser HI, Dendrou CA, Healy B, Rainbow DB, Howlett S et al.

    Journal of immunology (Baltimore, Md. : 1950) 2010;184;9;5075-84

  • Genome-wide end-sequenced BAC resources for the NOD/MrkTac() and NOD/ShiLtJ() mouse genomes.

    Steward CA, Humphray S, Plumb B, Jones MC, Quail MA et al.

    Genomics 2010;95;2;105-10

  • The consensus coding sequence (CCDS) project: Identifying a common protein-coding gene set for the human and mouse genomes.

    Pruitt KD, Harrow J, Harte RA, Wallin C, Diekhans M et al.

    Genome research 2009;19;7;1316-23

  • Conservation of the H19 noncoding RNA and H19-IGF2 imprinting mechanism in therians.

    Smits G, Mungall AJ, Griffiths-Jones S, Smith P, Beury D et al.

    Nature genetics 2008;40;8;971-6

  • The evolution of the DLK1-DIO3 imprinted domain in mammals.

    Edwards CA, Mungall AJ, Matthews L, Ryder E, Gray DJ et al.

    PLoS biology 2008;6;6;e135

  • The DNA sequence and biological annotation of human chromosome 1.

    Gregory SG, Barlow KF, McLay KE, Kaul R, Swarbreck D et al.

    Nature 2006;441;7091;315-21

  • DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

    Zody MC, Garber M, Adams DJ, Sharpe T, Harrow J et al.

    Nature 2006;440;7087;1045-9

  • Genomic anatomy of the Tyrp1 (brown) deletion complex.

    Smyth IM, Wilming L, Lee AW, Taylor MS, Gautier P et al.

    Proceedings of the National Academy of Sciences of the United States of America 2006;103;10;3704-9

  • The DNA sequence of the human X chromosome.

    Ross MT, Grafham DV, Coffey AJ, Scherer S, McLay K et al.

    Nature 2005;434;7031;325-37

  • Finishing the euchromatic sequence of the human genome.

    International Human Genome Sequencing Consortium

    Nature 2004;431;7011;931-45

  • Integrative annotation of 21,037 human genes validated by full-length cDNA clones.

    Imanishi T, Itoh T, Suzuki Y, O'Donovan C, Fukuchi S et al.

    PLoS biology 2004;2;6;e162

  • The DNA sequence and comparative analysis of human chromosome 10.

    Deloukas P, Earthrowl ME, Grafham DV, Rubenfield M, French L et al.

    Nature 2004;429;6990;375-81

  • DNA sequence and analysis of human chromosome 9.

    Humphray SJ, Oliver K, Hunt AR, Plumb RW, Loveland JE et al.

    Nature 2004;429;6990;369-74

  • The DNA sequence and analysis of human chromosome 13.

    Dunham A, Matthews LH, Burton J, Ashurst JL, Howe KL et al.

    Nature 2004;428;6982;522-8

  • The DNA sequence and analysis of human chromosome 6.

    Mungall AJ, Palmer SA, Sims SK, Edwards CA, Ashurst JL et al.

    Nature 2003;425;6960;805-11

  • The DNA sequence and comparative analysis of human chromosome 20.

    Deloukas P, Matthews LH, Ashurst J, Burton J, Gilbert JG et al.

    Nature 2001;414;6866;865-71

  • Initial sequencing and analysis of the human genome.

    Lander ES, Linton LM, Birren B, Nusbaum C, Zody MC et al.

    Nature 2001;409;6822;860-921

  • An SNP map of human chromosome 22.

    Mullikin JC, Hunt SE, Cole CG, Mortimore BJ, Rice CM et al.

    Nature 2000;407;6803;516-20

  • The DNA sequence of human chromosome 22.

    Dunham I, Shimizu N, Roe BA, Chissoe S, Hunt AR et al.

    Nature 1999;402;6761;489-95

  • How the worm was won. The C. elegans genome sequencing project.

    Wilson RK

    Trends in genetics : TIG 1999;15;2;51-8

Steward, Charles Andrew