I am a Postdoctoral Fellow working in the field of immunogenetics. I use immune receptor sequencing to understand the evolution of antigen-specific responses to different antigens in infection, vaccination and autoimmunity.
My background is in the fields of immunology and infectious diseases. During my PhD, I worked on the development of methods for B-cell receptor sequencing, which I then applied in the context of virus infection and vaccination. My current postdoctoral work focuses on the investigation of antigen reactivity driving chronic inflammation in inflammatory bowel disease. In addition to my employment at the Wellcome Sanger Insitute, I am a Borysiewicz Fellow at the University of Cambridge. As part of this fellowship, I am working on a project inspired by one of the UN sustainable development goals which combines research and global health policy in the area of infectious diseases.
The evolution of seasonal influenza viruses.
Nature reviews. Microbiology 2018;16;1;47-60
Deep sequencing of norovirus genomes defines evolutionary patterns in an urban tropical setting.
Journal of virology 2014;88;19;11056-69
Host genetic variants and gene expression patterns associated with Epstein-Barr virus copy number in lymphoblastoid cell lines.
PloS one 2014;9;10;e108384
Full-genome deep sequencing and phylogenetic analysis of novel human betacoronavirus.
Emerging infectious diseases 2013;19;5;736-42B
Genome watch: The chronicles of virus-host affairs.
Nature reviews. Microbiology 2015;13;8;460