Dr David Parry-Smith | Senior Scientific Manager

Parry-Smith, David

Dr Parry-Smith leads the Stem Cell Informatics Team. His role is to interact with scientists at all levels, understand and gather requirements for developing and maintaining informatics systems supporting Stem Cell Engineering. He is a biophysicist software developer interested in bioinformatics of genome editing using CRISPR/Cas9 (see WGE), algorithms for tracking lab processes and sequence pattern recognition.


  • Exploiting induced pluripotent stem cell-derived macrophages to unravel host factors influencing Chlamydia trachomatis pathogenesis.

    Yeung ATY, Hale C, Lee AH, Gill EE, Bushell W et al.

    Nature communications 2017;8;15013

  • WGE: a CRISPR database for genome engineering.

    Hodgkins A, Farne A, Perera S, Grego T, Parry-Smith DJ et al.

    Bioinformatics (Oxford, England) 2015;31;18;3078-80

  • CINEMA--a novel colour INteractive editor for multiple alignments.

    Parry-Smith DJ, Payne AW, Michie AD and Attwood TK

    Gene 1998;221;1;GC57-63

  • Phylogenomic analysis and evolution of the potassium channel gene family.

    Moulton G, Attwood TK, Parry-Smith DJ and Packer JC

    Receptors & channels 2003;9;6;363-77

  • The PRINTS database of protein fingerprints: a novel information resource for computational molecular biology.

    Attwood TK, Avison H, Beck ME, Bewley M, Bleasby AJ et al.

    Journal of chemical information and computer sciences 1997;37;3;417-24

  • PRINTS--a database of protein motif fingerprints.

    Attwood TK, Beck ME, Bleasby AJ and Parry-Smith DJ

    Nucleic acids research 1994;22;17;3590-6

  • ADSP--a new package for computational sequence analysis.

    Parry-Smith DJ and Attwood TK

    Computer applications in the biosciences : CABIOS 1992;8;5;451-9

  • SOMAP: a novel interactive approach to multiple protein sequences alignment.

    Parry-Smith DJ and Attwood TK

    Computer applications in the biosciences : CABIOS 1991;7;2;233-5

  • Dietary intake measurement using 7 d diet diaries in British men and women in the European Prospective Investigation into Cancer-Norfolk study: a focus on methodological issues.

    Lentjes MA, McTaggart A, Mulligan AA, Powell NA, Parry-Smith D et al.

    The British journal of nutrition 2014;111;3;516-26

  • Cloning and pharmacological characterization of human alpha-1 adrenergic receptors: sequence corrections and direct comparison with other species homologues.

    Schwinn DA, Johnston GI, Page SO, Mosley MJ, Wilson KH et al.

    The Journal of pharmacology and experimental therapeutics 1995;272;1;134-42

  • A new tool for converting food frequency questionnaire data into nutrient and food group values: FETA research methods and availability.

    Mulligan AA, Luben RN, Bhaniani A, Parry-Smith DJ, O'Connor L et al.

    BMJ open 2014;4;3;e004503

Parry-Smith, David
David's Timeline

Senior Scientific Manager, Stem Cell Informatics, Scientific Operations, Wellcome Trust Sanger Institute


Senior LIMS Developer, Stem Cell Engineering, Skarnes Faculty, Wellcome Trust Sanger Institute


Senior Software Developer, High-Throughput Gene Targeting, Skarnes Faculty, Wellcome Trust Sanger Institute


Cambridge Nutrition Centre (CNC) Programmer, Dept of Public Health and Primary Care, University of Cambridge European Prospective Investigation into Cancer (EPIC)


Target Discovery Consultant, ChiBio Informatics Limited, Cambridge


Chief Executive, Purely Proteins Limited, Cambridge


Chief Operating Officer, Purely Proteins Limited, Cambridge


Informatics Director Cambridge Drug Discovery Limited (later, BioFocus PLC)


Principal Scientist, Bioinformatics Group Leader, Pfizer Central Research, Sandwich, Kent UK


PhD, Astbury Dept of Biophysics, University of Leeds, UK


Post-doctoral Fellowship, Dept of Genetics, University of Leeds UK


BSc(hons) 4Yr Biophysics, Astbury Department of Biophysics, University of Leeds, UK