Mihir Kekre | Operations Lead - Next-Gen Sequencing & Global Capacity Building

Kekre, Mihir

The NIHR Global Health Research Unit (GHRU) for Genomic Surveillance of Antimicrobial Resistance (http://ghru.pathogensurveillance.net)  is working with partners in four countries to develop a suite a tools that provide an efficient pathway to building genomics capacity, specially focussing on AMR. The success of this international initiative revolves around four crucial pillars:

- Growing a global AMR network in low and middle-income countries (LMIC).

- Building genomic surveillance capacity in these LMIC laboratories through cost-effective, high throughput, high-quality sequencing workflows

- Generating actionable data

- Enabling regional and national programmes to leverage the power of this data, thereby improving public health decisions.

Publications

  • K13-propeller polymorphisms in Plasmodium falciparum parasites from sub-Saharan Africa.

    Kamau E, Campino S, Amenga-Etego L, Drury E, Ishengoma D et al.

    The Journal of infectious diseases 2015;211;8;1352-5

  • Optimized whole-genome amplification strategy for extremely AT-biased template.

    Oyola SO, Manske M, Campino S, Claessens A, Hamilton WL et al.

    DNA research : an international journal for rapid publication of reports on genes and genomes 2014;21;6;661-71

  • Generation of antigenic diversity in Plasmodium falciparum by structured rearrangement of Var genes during mitosis.

    Claessens A, Hamilton WL, Kekre M, Otto TD, Faizullabhoy A et al.

    PLoS genetics 2014;10;12;e1004812

  • Genomic epidemiology of artemisinin resistant malaria.

    MalariaGEN Plasmodium falciparum Community Project

    eLife 2016;5

  • Whole genome sequencing of Plasmodium falciparum from dried blood spots using selective whole genome amplification.

    Oyola SO, Ariani CV, Hamilton WL, Kekre M, Amenga-Etego LN et al.

    Malaria journal 2016;15;1;597

  • Extreme mutation bias and high AT content in Plasmodium falciparum.

    Hamilton WL, Claessens A, Otto TD, Kekre M, Fairhurst RM et al.

    Nucleic acids research 2017;45;4;1889-1901

  • Genomic analysis of local variation and recent evolution in Plasmodium vivax.

    Pearson RD, Amato R, Auburn S, Miotto O, Almagro-Garcia J et al.

    Nature genetics 2016;48;8;959-964

  • Mapping imported malaria in Bangladesh using parasite genetic and human mobility data.

    Chang HH, Wesolowski A, Sinha I, Jacob CG, Mahmud A et al.

    eLife 2019;8

  • Mapping imported malaria in Bangladesh using parasite genetic and human mobility data.

    Chang HH, Wesolowski A, Sinha I, Jacob CG, Mahmud A et al.

    eLife 2019;8

  • Extreme mutation bias and high AT content in Plasmodium falciparum.

    Hamilton WL, Claessens A, Otto TD, Kekre M, Fairhurst RM et al.

    Nucleic acids research 2017;45;4;1889-1901

  • Whole genome sequencing of Plasmodium falciparum from dried blood spots using selective whole genome amplification.

    Oyola SO, Ariani CV, Hamilton WL, Kekre M, Amenga-Etego LN et al.

    Malaria journal 2016;15;1;597

  • Genomic analysis of local variation and recent evolution in Plasmodium vivax.

    Pearson RD, Amato R, Auburn S, Miotto O, Almagro-Garcia J et al.

    Nature genetics 2016;48;8;959-964

  • Genomic epidemiology of artemisinin resistant malaria.

    MalariaGEN Plasmodium falciparum Community Project

    eLife 2016;5

  • K13-propeller polymorphisms in Plasmodium falciparum parasites from sub-Saharan Africa.

    Kamau E, Campino S, Amenga-Etego L, Drury E, Ishengoma D et al.

    The Journal of infectious diseases 2015;211;8;1352-5

  • Generation of antigenic diversity in Plasmodium falciparum by structured rearrangement of Var genes during mitosis.

    Claessens A, Hamilton WL, Kekre M, Otto TD, Faizullabhoy A et al.

    PLoS genetics 2014;10;12;e1004812

  • Optimized whole-genome amplification strategy for extremely AT-biased template.

    Oyola SO, Manske M, Campino S, Claessens A, Hamilton WL et al.

    DNA research : an international journal for rapid publication of reports on genes and genomes 2014;21;6;661-71

Kekre, Mihir
Mihir's Timeline
2018

Operations Lead - Next-gen Sequencing and Global Capacity Building

2017

Product Lead - Whole-genome and Exome Sequencing

2014

MalariaGEN Pipelines Manager

2012

Advanced Research Assistant - Transmission dynamics of P. falciparum