Martin Del Castillo Velasco Herrera | Postdoctoral Fellow

This person is a member of Sanger Institute Alumni.

Del Castillo Velasco Herrera, Martin

I am a genomicist interested in understanding the role of the genetic alterations that cells acquire throughout cancer development as well as the cellular composition at the single cell level.

Publications

  • Recurrent intragenic rearrangements of EGFR and BRAF in soft tissue tumors of infants.

    Wegert J, Vokuhl C, Collord G, Del Castillo Velasco-Herrera M, Farndon SJ et al.

    Nature communications 2018;9;1;2378

  • Single-cell transcriptomes from human kidneys reveal the cellular identity of renal tumors.

    Young MD, Mitchell TJ, Vieira Braga FA, Tran MGB, Stewart BJ et al.

    Science (New York, N.Y.) 2018;361;6402;594-599

  • Genome-wide recessive genetic screening in mammalian cells with a lentiviral CRISPR-guide RNA library.

    Koike-Yusa H, Li Y, Tan EP, Velasco-Herrera Mdel C and Yusa K

    Nature biotechnology 2014;32;3;267-73

  • Genome-wide in vivo screen identifies novel host regulators of metastatic colonization.

    van der Weyden L, Arends MJ, Campbell AD, Bald T, Wardle-Jones H et al.

    Nature 2017;541;7636;233-236

  • Comparative genomics reveals that loss of lunatic fringe (LFNG) promotes melanoma metastasis.

    Del Castillo Velasco-Herrera M, van der Weyden L, Nsengimana J, Speak AO, Sjöberg MK et al.

    Molecular oncology 2018;12;2;239-255

  • The BRAF pseudogene functions as a competitive endogenous RNA and induces lymphoma in vivo.

    Karreth FA, Reschke M, Ruocco A, Ng C, Chapuy B et al.

    Cell 2015;161;2;319-32

  • Single-cell transcriptomes from human kidneys reveal the cellular identity of renal tumors.

    Young MD, Mitchell TJ, Vieira Braga FA, Tran MGB, Stewart BJ et al.

    Science (New York, N.Y.) 2018;361;6402;594-599

  • Recurrent intragenic rearrangements of EGFR and BRAF in soft tissue tumors of infants.

    Wegert J, Vokuhl C, Collord G, Del Castillo Velasco-Herrera M, Farndon SJ et al.

    Nature communications 2018;9;1;2378

  • Comparative genomics reveals that loss of lunatic fringe (LFNG) promotes melanoma metastasis.

    Del Castillo Velasco-Herrera M, van der Weyden L, Nsengimana J, Speak AO, Sjöberg MK et al.

    Molecular oncology 2018;12;2;239-255

  • Genomic Determinants of Protein Abundance Variation in Colorectal Cancer Cells.

    Roumeliotis TI, Williams SP, Gonçalves E, Alsinet C, Del Castillo Velasco-Herrera M et al.

    Cell reports 2017;20;9;2201-2214

  • Revisiting olfactory receptors as putative drivers of cancer.

    Ranzani M, Iyer V, Ibarra-Soria X, Del Castillo Velasco-Herrera M, Garnett M et al.

    Wellcome open research 2017;2;9

  • Genome-wide in vivo screen identifies novel host regulators of metastatic colonization.

    van der Weyden L, Arends MJ, Campbell AD, Bald T, Wardle-Jones H et al.

    Nature 2017;541;7636;233-236

  • Early maturation and distinct tau pathology in induced pluripotent stem cell-derived neurons from patients with MAPT mutations.

    Iovino M, Agathou S, González-Rueda A, Del Castillo Velasco-Herrera M, Borroni B et al.

    Brain : a journal of neurology 2015;138;Pt 11;3345-59

  • The BRAF pseudogene functions as a competitive endogenous RNA and induces lymphoma in vivo.

    Karreth FA, Reschke M, Ruocco A, Ng C, Chapuy B et al.

    Cell 2015;161;2;319-32

  • Off-target assessment of CRISPR-Cas9 guiding RNAs in human iPS and mouse ES cells.

    Tan EP, Li Y, Velasco-Herrera Mdel C, Yusa K and Bradley A

    Genesis (New York, N.Y. : 2000) 2015;53;2;225-36

  • Telomere-regulating genes and the telomere interactome in familial cancers.

    Robles-Espinoza CD, Velasco-Herrera Mdel C, Hayward NK and Adams DJ

    Molecular cancer research : MCR 2015;13;2;211-22

  • Reconstructing and mining the B cell repertoire with ImmunediveRsity.

    Cortina-Ceballos B, Godoy-Lozano EE, Sámano-Sánchez H, Aguilar-Salgado A, Velasco-Herrera Mdel C et al.

    mAbs 2015;7;3;516-24

  • Genome-wide recessive genetic screening in mammalian cells with a lentiviral CRISPR-guide RNA library.

    Koike-Yusa H, Li Y, Tan EP, Velasco-Herrera Mdel C and Yusa K

    Nature biotechnology 2014;32;3;267-73

  • Jdp2 downregulates Trp53 transcription to promote leukaemogenesis in the context of Trp53 heterozygosity.

    van der Weyden L, Rust AG, McIntyre RE, Robles-Espinoza CD, del Castillo Velasco-Herrera M et al.

    Oncogene 2013;32;3;397-402

  • Disruption of mouse Cenpj, a regulator of centriole biogenesis, phenocopies Seckel syndrome.

    McIntyre RE, Lakshminarasimhan Chavali P, Ismail O, Carragher DM, Sanchez-Andrade G et al.

    PLoS genetics 2012;8;11;e1003022

Del Castillo Velasco Herrera, Martin
Martin's Timeline
2012

Started PhD at the University of Cambridge

2011

Obtained BSc(Hons) in Genome Sciences from the National Autonomous University of Mexico