Dr Mukul Rawat

Postdoctoral Fellow

My research interest revolves around understanding the transcriptional regulation of resistance in Plasmodium falciparum. Emergence of resistance requires stringent transcriptional regulation, which in turn is dictated by various key molecular players. Deciphering the role of these molecules can open up more avenue for the development of malaria transmission blocking intervention strategies.

I completed my PhD  at Indian Institute of Science Education and Research (IISER), Pune India and conducted my thesis work in the lab of Dr. Krishanpal Karmodiya. There I focussed on deciphering the role of epigenetic gene regulation in mediating stress responses and artemisinin-resistance in the malaria parasite. For my post-doctoral research I intend to leverage my expertise in epigenetic and genome editing to more deeply understand the process of transcriptional regulation in drug resistance in Plasmodium falciparum. Identifying new antimalarial candidates and studying their cellular targets, underlying resistance mechanism and measuring fitness cost associated with resistance can help us in controlling and eradicating malaria globally.

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