Sumana Sharma
PhD Student
Alumni
This person is a member of Sanger Institute Alumni.
Sumana is a PhD student working on developing methods to identify and validate protein interactions between Plasmodium merozoites and human host cells, which are required for the pathogenenis of malaria.
I am interested in understanding the molecular mechanisms behind the invasion of human host erythrocytes by Plasmodium parasites. This process involves many host-parasite protein-protein interactions but very few of these are known to date. Currently, I am developing a CRISPR/Cas9 based cellular screen to identify novel low affinity receptor ligand interactions using highly avid recombinant proteins and the resources developed by Kosuke Yusa for genome-wide recessive screens.
My timeline
Joined the Wellcome Trust PhD program
Completed M.Sc degree in Molecular Biology from International Max Planck Research School, Goettingen University, Germany
Started an external M.Sc thesis project with Dr. Julian Rayner on identification and characterization of protein interaction in Plasmodium falciparum.
Completed B.Sc degree in Biochemistry and Cell Biology from Jacobs Univeristy Bremen, Germany