This person is a member of Sanger Institute Alumni.

Sumana is a PhD student working on developing methods to identify and validate protein interactions between Plasmodium merozoites and human host cells, which are required for the pathogenenis of malaria.

I am interested in understanding the molecular mechanisms behind the invasion of human host erythrocytes by Plasmodium parasites. This process involves many host-parasite protein-protein interactions but very few of these are known to date. Currently, I am developing a CRISPR/Cas9 based cellular screen to identify novel low affinity receptor ligand interactions using highly avid recombinant proteins and the resources developed by Kosuke Yusa for genome-wide recessive screens.

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