Archive Page: Palotie Group | Genetics of common neurological diseases

Archive Page: Palotie Group | Genetics of common neurological diseases

Palotie Group

This page is being kept as a historical record of the research conducted at the Sanger Institute. This page is no longer being updated and was last edited Summer 2013.

Our Research and Approach

Please note: This page is no longer being updated.

From Autumn 2007 to Summer 2013, Professor Aarno led the Genomics of common neurological disorders group at the Wellcome Trust Sanger Institute which mainly investigated the genetic predisposition of traits affecting the Central Nervous System, particularly migraine, epilepsy, schizophrenia and autism.

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  • The GENCODE exome: sequencing the complete human exome.

    Coffey AJ, Kokocinski F, Calafato MS, Scott CE, Palta P et al.

    European journal of human genetics : EJHG 2011;19;7;827-31

  • Genome-wide association study reveals three susceptibility loci for common migraine in the general population.

    Chasman DI, Schürks M, Anttila V, de Vries B, Schminke U et al.

    Nature genetics 2011;43;7;695-8

  • Genome-wide association study of migraine implicates a common susceptibility variant on 8q22.1.

    Anttila V, Stefansson H, Kallela M, Todt U, Terwindt GM et al.

    Nature genetics 2010;42;10;869-73

  • Integrating common and rare genetic variation in diverse human populations.

    International HapMap 3 Consortium, Altshuler DM, Gibbs RA, Peltonen L, Altshuler DM et al.

    Nature 2010;467;7311;52-8

  • An immune response network associated with blood lipid levels.

    Inouye M, Silander K, Hamalainen E, Salomaa V, Harald K et al.

    PLoS genetics 2010;6;9;e1001113

  • Distinct variants at LIN28B influence growth in height from birth to adulthood.

    Widén E, Ripatti S, Cousminer DL, Surakka I, Lappalainen T et al.

    American journal of human genetics 2010;86;5;773-82

  • Target-enrichment strategies for next-generation sequencing.

    Mamanova L, Coffey AJ, Scott CE, Kozarewa I, Turner EH et al.

    Nature methods 2010;7;2;111-8

  • Donor-recipient mismatch for common gene deletion polymorphisms in graft-versus-host disease.

    McCarroll SA, Bradner JE, Turpeinen H, Volin L, Martin PJ et al.

    Nature genetics 2009;41;12;1341-4

  • The genome-wide patterns of variation expose significant substructure in a founder population.

    Jakkula E, Rehnström K, Varilo T, Pietiläinen OP, Paunio T et al.

    American journal of human genetics 2008;83;6;787-94

  • Susceptibility loci for intracranial aneurysm in European and Japanese populations.

    Bilguvar K, Yasuno K, Niemelä M, Ruigrok YM, von Und Zu Fraunberg M et al.

    Nature genetics 2008;40;12;1472-7

  • A high-density association screen of 155 ion transport genes for involvement with common migraine.

    Nyholt DR, LaForge KS, Kallela M, Alakurtti K, Anttila V et al.

    Human molecular genetics 2008;17;21;3318-31

  • Consistently replicating locus linked to migraine on 10q22-q23.

    Anttila V, Nyholt DR, Kallela M, Artto V, Vepsäläinen S et al.

    American journal of human genetics 2008;82;5;1051-63