GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Parkinson's disease

The human homologues of the following genes have been identified in "Parkinson's disease" studies:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
acmsd ACMSD ENSDARG00000062549 None Not determined 2
bmp4 BMP4 ENSDARG00000019995 1 Not determined 4
BST1 BST1 ENSDARG00000086451 None Not determined 4
cnnm2a CNNM2 ENSDARG00000061195 2 Not determined 9
cnnm2b CNNM2 ENSDARG00000078733 1 Not determined 9
cyp17a1 CYP17A1 ENSDARG00000033566 3 Not determined 7
cyp17a2 CYP17A1 ENSDARG00000053966 None Not determined 7
dlg2 DLG2 ENSDARG00000076691 2 Not determined 5
gak GAK ENSDARG00000094483 None Not determined 5
GAK (2 of 3) GAK ENSDARG00000090654 None Not determined 5
hip1r CCDC62 ENSDARG00000077445 1 Not determined 1
HIP1R (2 of 2) HIP1R ENSDARG00000060627 2 Not determined 1
KIAA1267 (2 of 2) KIAA1267 ENSDARG00000090895 4 Not determined 1
KIAA1267 (1 of 2) KIAA1267 ENSDARG00000088238 1 Not determined 1
LOC100151158 GAK ENSDARG00000039384 None Not determined 5
LOC100329499 UNC13B ENSDARG00000086274 4 Not determined 1
LOC100329854 STK39 ENSDARG00000087203 1 Not determined 2
LOC100333007 RAI1 ENSDARG00000076679 None Not determined 1
LOC100333241 KIAA1267 ENSDARG00000086284 None Not determined 1
LOC100334375 DBC1 ENSDARG00000078302 2 Not determined 2
LOC560882 RAI1 ENSDARG00000086459 None Not determined 1
LOC566255 MMRN1 ENSDARG00000073711 1 Not determined 1
LOC792854 STBD1 ENSDARG00000086641 1 Not determined 1
LRRK2 LRRK2 ENSDARG00000006169 6 Not determined 8
MAPT (2 of 2) MAPT ENSDARG00000087616 3 Not determined 11
mapta MAPT ENSDARG00000089314 2 Not determined 11
mhc2dab HLA-DRB5 ENSDARG00000079105 None Not determined 6
NP_001091732.1 HLA-DRB5 ENSDARG00000071168 1 Not determined 6
nsfa NSF ENSDARG00000007654 3 Not determined 2
nsfb NSF ENSDARG00000038991 4 Not determined 2
nucks1b NUCKS1 ENSDARG00000012777 1 Not determined 4
pm20d1.1 PM20D1 ENSDARG00000037551 1 Not determined 1
pm20d1.2 PM20D1 ENSDARG00000062096 None Not determined 1
prdm15 PRDM15 ENSDARG00000091516 None Not determined 2
PRDM15 (2 of 2) PRDM15 ENSDARG00000087972 None Not determined 2
RAI1 (3 of 3) RAI1 ENSDARG00000090142 None Not determined 1
scarb2 SCARB2 ENSDARG00000086099 None Not determined 1
scarb2 SCARB2 ENSDARG00000086371 None Not determined 1
SCARB2 SCARB2 ENSDARG00000089844 None Not determined 1
sema5a SEMA5A ENSDARG00000058821 6 Not determined 4
sfxn2 SFXN2 ENSDARG00000017960 None Not determined 1
sh3gl2 SH3GL2 ENSDARG00000023600 2 Not determined 5
SH3GL2 (1 of 2) SH3GL2 ENSDARG00000039901 None Not determined 5
si:busm1-104n07.3 HLA-DRB5 ENSDARG00000074510 1 Normal 6
si:busm1-160c18.1 HLA-DRA ENSDARG00000053739 2 Not determined 21
si:busm1-160c18.3 HLA-DRB5 ENSDARG00000053738 None Not determined 6
si:busm1-160c18.3 HLA-DRB5 ENSDARG00000093706 None Not determined 6
si:busm1-194e12.11 HLA-DRA ENSDARG00000055441 1 Not determined 21
si:busm1-194e12.12 HLA-DRB5 ENSDARG00000055447 None Not determined 6
si:busm1-228j01.3 HLA-DRA ENSDARG00000086294 2 Not determined 21
si:busm1-228j01.4 HLA-DRB5 ENSDARG00000088872 2 Not determined 6
si:busm1-228j01.5 HLA-DRA ENSDARG00000079593 3 Not determined 21
si:busm1-228j01.6 HLA-DRB5 ENSDARG00000041705 1 Not determined 6
si:ch1073-167a23.1 PLEKHM1 ENSDARG00000094420 None Not determined 1
si:ch1073-403i13.1 HLA-DRA ENSDARG00000001832 None Not determined 21
si:ch211-134m17.7 MMRN1 ENSDARG00000076135 4 Not determined 1
si:ch73-211l2.3 HLA-DRA ENSDARG00000075932 1 Not determined 21
si:ch73-6o20.1 UNC13B ENSDARG00000017391 3 Not determined 1
si:dkey-19n13.4 GBA ENSDARG00000076058 1 Normal 3
si:dkeyp-2h4.2 HLA-DRA ENSDARG00000031745 None Not determined 21
si:zfos-2070c2.1 HLA-DRA ENSDARG00000070206 None Not determined 21
si:zfos-2070c2.3 HLA-DRB5 ENSDARG00000076307 None Not determined 6
si:zfos-367g9.1 HLA-DRA ENSDARG00000074816 1 Not determined 21
SLC2A13 (3 of 3) SLC2A13 ENSDARG00000037448 None Not determined 1
SLC2A13 (2 of 3) SLC2A13 ENSDARG00000076899 1 Not determined 1
SLC2A13 (1 of 3) SLC2A13 ENSDARG00000087867 None Not determined 1
slc41a1 SLC41A1 ENSDARG00000070214 1 Not determined 3
slc45a3 SLC45A3 ENSDARG00000075975 4 Not determined 3
srebf1 SREBF1 ENSDARG00000067607 2 Not determined 1
STK39 (2 of 2) STK39 ENSDARG00000088508 1 Not determined 2
syt11a SYT11 ENSDARG00000057913 1 Not determined 1
syt11b SYT11 ENSDARG00000056105 1 Not determined 1
syt4 SYT4 ENSDARG00000036505 None Not determined 1
tas1r2.1 TAS1R2 ENSDARG00000053135 2 Not determined 1
tas1r2.2 TAS1R2 ENSDARG00000059397 4 Not determined 1
usp25 USP25 ENSDARG00000012314 6 Not determined 2
wnt3 WNT3 ENSDARG00000038990 None Not determined 2
wu:fc07e02 NUCKS1 ENSDARG00000078473 2 Not determined 4
wu:fd58b11 HLA-DRB5 ENSDARG00000054921 None Not determined 6
zgc:114169 C10orf32 ENSDARG00000055070 None Not determined 1
zgc:123107 HLA-DRA ENSDARG00000020286 None Not determined 21
zgc:153067 HLA-DRB5 ENSDARG00000056330 2 Not determined 6
zgc:154018 CNKSR3 ENSDARG00000068613 3 Not determined 2
zgc:154106 MCCC1 ENSDARG00000054046 None Not determined 2
zgc:158281 PLEKHM1 ENSDARG00000063247 1 Not determined 1
zgc:158784 HIP1R ENSDARG00000059484 5 Not determined 1
zgc:172112 CNKSR3 ENSDARG00000074236 3 Not determined 2
zgc:172265 ITGA8 ENSDARG00000078717 9 Not determined 2
zgc:77158 SLC45A3 ENSDARG00000013784 2 Not determined 3

The following reported genes could not be linked automatically to a zebrafish gene:

  • BRDG1
  • C17orf69
  • C20orf82
  • DGKQ
  • DGKQ
  • DGKQ
  • IMP5
  • LAMP3
  • LAMP3
  • LOC642072
  • LOC644246
  • PARK16
  • PARK16
  • POL3S
  • RAB7L1
  • RIT2
  • RIT2
  • SNCA
  • SNCA
  • SNCA
  • SNCA
  • SNCA
  • SNCA
  • SNCA
  • SNCA
  • SNCA
  • SNCA
  • SNCA
  • STH
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