GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Metabolite levels

The human homologues of the following genes have been identified in "Metabolite levels" studies:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
A8WFQ6_DANRE SLC25A1 ENSDARG00000076381 None Not determined 2
abca1a ABCA1 ENSDARG00000074635 9 Not determined 13
acadl ACADL ENSDARG00000088357 1 Not determined 2
acadm ACADM ENSDARG00000038900 4 Not determined 2
acads ACADS ENSDARG00000030781 None Not determined 2
agxt2 AGXT2 ENSDARG00000087194 2 Not determined 2
aldh1l1 ALDH1L1 ENSDARG00000077004 6 Not determined 1
angptl3 ANGPTL3 ENSDARG00000044365 None Not determined 7
apoa1 APOA5 ENSDARG00000012076 1 Not determined 22
apoa1 APOA1 ENSDARG00000012076 1 Not determined 13
apoa1 APOA4 ENSDARG00000012076 1 Not determined 11
apoa4 APOA1 ENSDARG00000040298 1 Not determined 13
apoa4 APOA4 ENSDARG00000040298 1 Not determined 11
apoa4 APOA5 ENSDARG00000040298 1 Not determined 22
apob APOB ENSDARG00000042780 9 Not determined 17
apobl APOB ENSDARG00000022767 11 Not determined 17
apoeb APOE ENSDARG00000040295 1 Not determined 42
aqp9b AQP9 ENSDARG00000053480 1 Not determined 1
atp2b2 ATP2B2 ENSDARG00000063433 None Not determined 1
bhmt BHMT2 ENSDARG00000013430 1 Not determined 1
bhmt BHMT ENSDARG00000013430 1 Not determined 1
ccnb2 CCNB2 ENSDARG00000036180 None Not determined 1
cetp CETP ENSDARG00000030872 2 Not determined 27
CLTCL1 (2 of 2) CLTCL1 ENSDARG00000088853 1 Not determined 1
CLTCL1 (1 of 2) CLTCL1 ENSDARG00000091618 5 Not determined 1
cyp4v2 CYP4V2 ENSDARG00000062132 None Not determined 1
dhx38 DHX38 ENSDARG00000053946 3 Not determined 2
dock7 DOCK7 ENSDARG00000078675 4 Not determined 5
dusp11 DUSP11 ENSDARG00000038156 1 Not determined 2
elovl2 ELOVL2 ENSDARG00000045414 2 Not determined 4
etfdh ETFDH ENSDARG00000038834 None Not determined 2
fads2 FADS2 ENSDARG00000019532 None Not determined 15
fen1 FEN1 ENSDARG00000011404 4 Not determined 4
fgf12 FGF12 ENSDARG00000027957 None Not determined 3
gc GC ENSDARG00000089310 1 Not determined 5
gc ALB ENSDARG00000089310 1 Not determined 1
gls2 GLS2 ENSDARG00000069095 1 Not determined 3
gltpd2 GLTPD2 ENSDARG00000067889 1 Not determined 1
GPC5 GPC5 ENSDARG00000088858 1 Not determined 9
grk5 GRK6 ENSDARG00000032801 None Not determined 3
GSC2 GSC2 ENSDARG00000076491 1 Not determined 1
id:ibd5037 SV2B ENSDARG00000063456 None Not determined 1
klf15 KLF15 ENSDARG00000091127 None Not determined 1
ldlr LDLR ENSDARG00000029476 3 Not determined 15
LDLR (2 of 2) LDLR ENSDARG00000089730 None Not determined 15
lipc LIPC ENSDARG00000053476 2 Not determined 24
LIPC (2 of 2) LIPC ENSDARG00000090486 None Not determined 24
lipg LIPG ENSDARG00000031044 2 Not determined 9
LOC100002437 GLTPD2 ENSDARG00000054218 1 Not determined 1
LOC100002956 NAT8 ENSDARG00000078991 None Not determined 5
LOC100004652 NAT8 ENSDARG00000077028 None Not determined 5
LOC100151141 RNF111 ENSDARG00000078802 4 Not determined 2
LOC100331214 LPL ENSDARG00000034667 None Not determined 21
LOC100332592 SLC6A13 ENSDARG00000067567 1 Not determined 2
LOC100332592 SLC6A12 ENSDARG00000067567 1 Not determined 2
LOC100333044 GCKR ENSDARG00000086620 None Not determined 39
LOC100334818 SLC2A4 ENSDARG00000001937 1 Not determined 2
LOC556200 KLF15 ENSDARG00000090914 None Not determined 1
LOC561288 GRK6 ENSDARG00000032157 2 Not determined 3
LOC562087 PPM1K ENSDARG00000076011 4 Normal 3
LOC568788 ADAMTS3 ENSDARG00000060127 4 Not determined 4
LOC797748 GLS2 ENSDARG00000062781 1 Not determined 3
lpl LPL ENSDARG00000087697 1 Not determined 21
LPL (1 of 2) LPL ENSDARG00000091659 2 Not determined 21
MR1BB_DANRE MTNR1B ENSDARG00000086493 None Not determined 15
mtnr1ba MTNR1B ENSDARG00000053833 None Not determined 15
mtnr1bb MTNR1B ENSDARG00000086883 None Not determined 15
myo1e MYO1E ENSDARG00000036179 6 Not determined 1
NP_001185674.1 TM4SF5 ENSDARG00000090943 1 Not determined 1
park2 PARK2 ENSDARG00000021555 1 Not determined 4
PCSK9 PCSK9 ENSDARG00000074185 1 Not determined 10
pfn1 PFN3 ENSDARG00000088091 None Not determined 3
phgdh PHGDH ENSDARG00000001873 2 Not determined 2
plek PLEK ENSDARG00000017298 1 Not determined 4
pltp PLTP ENSDARG00000035768 1 Not determined 5
PP1RB_DANRE PPP1R11 ENSDARG00000036063 None Not determined 1
ppm1k PPM1K ENSDARG00000010655 1 Not determined 3
ppp1r3b PPP1R3B ENSDARG00000044691 None Not determined 9
si:ch1073-189o9.1 MLXIPL ENSDARG00000089107 None Not determined 13
si:ch211-123f21.1 PARK2 ENSDARG00000091973 None Not determined 4
si:ch211-132b12.1 SLC6A13 ENSDARG00000061480 6 Not determined 2
si:ch211-132b12.1 SLC6A12 ENSDARG00000061480 6 Not determined 2
si:ch211-132b12.2 SLC6A13 ENSDARG00000094946 1 Not determined 2
si:ch211-132b12.2 SLC6A12 ENSDARG00000094946 1 Not determined 2
si:ch211-132b12.3 SLC6A13 ENSDARG00000068363 None Not determined 2
si:ch211-132b12.3 SLC6A12 ENSDARG00000068363 None Not determined 2
si:ch211-132b12.5 SLC6A13 ENSDARG00000068372 3 Not determined 2
si:ch211-132b12.5 SLC6A12 ENSDARG00000068372 3 Not determined 2
si:ch211-132b12.6 SLC6A12 ENSDARG00000094546 1 Not determined 2
si:ch211-132b12.6 SLC6A13 ENSDARG00000094546 1 Not determined 2
si:ch211-155m12.3 TNKS ENSDARG00000062897 3 Not determined 1
si:ch211-236l14.3 CPT1A ENSDARG00000062054 7 Not determined 2
si:ch211-257m21.2 USP24 ENSDARG00000059925 6 Not determined 1
si:ch211-272n13.3 ANKRD30A ENSDARG00000013015 3 Not determined 4
si:ch211-281g13.4 HERC6 ENSDARG00000075389 3 Not determined 1
si:ch211-281g13.5 HERC6 ENSDARG00000074052 2 Not determined 1
si:ch73-123i13.4 PYROXD2 ENSDARG00000014101 None Not determined 3
si:ch73-190m4.1 HERC6 ENSDARG00000075785 3 Not determined 1
si:ch73-386h18.1 ZFHX3 ENSDARG00000073944 7 Not determined 7
si:dkey-102c8.6 GLS2 ENSDARG00000002917 4 Not determined 3
si:dkey-162b3.1 GALNT2 ENSDARG00000003829 5 Not determined 8
si:dkey-178e17.1 SLC25A1 ENSDARG00000080000 1 Not determined 2
si:dkey-220o5.1 GRK6 ENSDARG00000078815 4 Not determined 3
si:dkey-225d17.3 CPS1 ENSDARG00000020028 6 Not determined 6
si:dkey-236e20.9 GPC5 ENSDARG00000024588 2 Not determined 9
si:dkey-242g16.2 PPP1R3B ENSDARG00000069377 None Not determined 9
si:dkey-258f14.3 LDLR ENSDARG00000075974 None Not determined 15
si:dkey-265c15.2 ALMS1 ENSDARG00000074779 5 Not determined 3
si:dkey-56p7.8 CPT1A ENSDARG00000059770 2 Not determined 2
si:dkey-7f3.15 APOA1 ENSDARG00000094929 3 Not determined 13
si:dkey-7f3.15 APOA4 ENSDARG00000094929 3 Not determined 11
si:dkey-7f3.15 APOA5 ENSDARG00000094929 3 Not determined 22
si:dkeyp-106c3.3 APOB ENSDARG00000093159 None Not determined 17
si:dkeyp-88f5.1 APOB ENSDARG00000075016 5 Not determined 17
slc16a10 SLC16A10 ENSDARG00000020984 1 Not determined 2
SLC16A10 (2 of 2) SLC16A10 ENSDARG00000089969 None Not determined 2
slc1a4 SLC1A4 ENSDARG00000000551 3 Not determined 2
slc25a1 SLC25A1 ENSDARG00000057110 2 Not determined 2
slc6a11 SLC6A12 ENSDARG00000074002 3 Not determined 2
slc6a11 SLC6A13 ENSDARG00000074002 3 Not determined 2
slc6a13 SLC6A12 ENSDARG00000000730 1 Not determined 2
slc6a13 SLC6A13 ENSDARG00000000730 1 Not determined 2
slc6a13l SLC6A13 ENSDARG00000001354 5 Not determined 2
slc6a13l SLC6A12 ENSDARG00000001354 5 Not determined 2
slco1d1 SLCO1B1 ENSDARG00000060181 2 Not determined 7
spryd4 SPRYD4 ENSDARG00000023309 None Not determined 1
sv2b SV2B ENSDARG00000090540 None Not determined 1
SV2B (1 of 3) SV2B ENSDARG00000060711 None Not determined 1
tat TAT ENSDARG00000069630 2 Not determined 2
tm4sf5 TM4SF5 ENSDARG00000055185 None Not determined 1
tnks TNKS ENSDARG00000077650 6 Not determined 1
tnks TNKS ENSDARG00000095261 1 Not determined 1
ugt1a5 UGT1A8 ENSDARG00000006220 6 Not determined 1
ugt1b4 UGT1A8 ENSDARG00000089507 2 Not determined 1
wu:fb81h03 ACE ENSDARG00000079166 5 Not determined 3
ZFHX3 ZFHX3 ENSDARG00000073681 11 Not determined 7
zgc:101896 TPRKB ENSDARG00000014941 None Not determined 2
zgc:110064 APOE ENSDARG00000086370 1 Not determined 42
zgc:112263 ELOVL2 ENSDARG00000057365 None Not determined 4
zgc:112374 PON1 ENSDARG00000040290 None Not determined 2
zgc:112484 CPT1A ENSDARG00000037943 4 Not determined 2
zgc:112992 APOA1 ENSDARG00000086281 None Not determined 13
zgc:112992 APOA4 ENSDARG00000086281 None Not determined 11
zgc:112992 APOA5 ENSDARG00000086281 None Not determined 22
zgc:153120 FGF12 ENSDARG00000062542 None Not determined 3
zgc:153394 ELOVL2 ENSDARG00000068551 2 Not determined 4
zgc:154042 CYP4V2 ENSDARG00000061585 1 Not determined 1
zgc:158677 SV2B ENSDARG00000057427 5 Not determined 1
zgc:162915 CYP4F2 ENSDARG00000053530 None Not determined 6
zgc:163136 HERC6 ENSDARG00000074136 2 Not determined 1
zgc:171581 ABCA1 ENSDARG00000079009 7 Not determined 13
zgc:194131 APOA1 ENSDARG00000020866 2 Not determined 13
zgc:194131 APOA4 ENSDARG00000020866 2 Not determined 11
zgc:194131 APOA5 ENSDARG00000020866 2 Not determined 22
zgc:64042 MYO1E ENSDARG00000009133 6 Not determined 1
zgc:77082 DHDPSL ENSDARG00000018944 None Not determined 1
zgc:77112 PPP1R3B ENSDARG00000015657 None Not determined 9
zgc:77556 PON1 ENSDARG00000016856 1 Not determined 2
zgc:91887 PON1 ENSDARG00000032496 None Not determined 2

The following reported genes could not be linked automatically to a zebrafish gene:

  • A2BP1
  • APOC1
  • APOC2
  • APOC3
  • APOC3
  • APOEC1
  • APOEC2
  • C10orf33
  • C20:2
  • C20:3
  • C6orf71
  • CXCL5
  • EREG
  • F12
  • F12
  • FADS1
  • FADS1
  • FADS1
  • FADS1
  • FADS1
  • FADS1
  • FADS3
  • FADS3
  • FADS3
  • FCGR2A
  • FCGR2B
  • G6PC2
  • G6PC2
  • HP
  • HPR
  • KLKB1
  • KLKB1
  • PDXC1
  • PF4
  • PPBP
  • SERPINA1
  • VM01
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