GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Genetic variants associated with glycine metabolism and their role in insulin sensitivity and type 2 diabetes.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
aldh1l1 ALDH1L1 ENSDARG00000077004 6 Not determined 1
bhmt BHMT2 ENSDARG00000013430 1 Not determined 1
bhmt BHMT ENSDARG00000013430 1 Not determined 1
fads2 FADS2 ENSDARG00000019532 None Not determined 15
fen1 FEN1 ENSDARG00000011404 4 Not determined 4
klf15 KLF15 ENSDARG00000091127 None Not determined 1
LOC100332592 SLC6A12 ENSDARG00000067567 1 Not determined 2
LOC100332592 SLC6A13 ENSDARG00000067567 1 Not determined 2
LOC556200 KLF15 ENSDARG00000090914 None Not determined 1
phgdh PHGDH ENSDARG00000001873 2 Not determined 2
si:ch211-132b12.1 SLC6A13 ENSDARG00000061480 6 Not determined 2
si:ch211-132b12.1 SLC6A12 ENSDARG00000061480 6 Not determined 2
si:ch211-132b12.2 SLC6A13 ENSDARG00000094946 1 Not determined 2
si:ch211-132b12.2 SLC6A12 ENSDARG00000094946 1 Not determined 2
si:ch211-132b12.3 SLC6A13 ENSDARG00000068363 None Not determined 2
si:ch211-132b12.3 SLC6A12 ENSDARG00000068363 None Not determined 2
si:ch211-132b12.5 SLC6A13 ENSDARG00000068372 3 Not determined 2
si:ch211-132b12.5 SLC6A12 ENSDARG00000068372 3 Not determined 2
si:ch211-132b12.6 SLC6A12 ENSDARG00000094546 1 Not determined 2
si:ch211-132b12.6 SLC6A13 ENSDARG00000094546 1 Not determined 2
si:dkey-225d17.3 CPS1 ENSDARG00000020028 6 Not determined 6
slc6a11 SLC6A13 ENSDARG00000074002 3 Not determined 2
slc6a11 SLC6A12 ENSDARG00000074002 3 Not determined 2
slc6a13 SLC6A12 ENSDARG00000000730 1 Not determined 2
slc6a13 SLC6A13 ENSDARG00000000730 1 Not determined 2
slc6a13l SLC6A12 ENSDARG00000001354 5 Not determined 2
slc6a13l SLC6A13 ENSDARG00000001354 5 Not determined 2

The following reported genes could not be linked automatically to a zebrafish gene:

  • FADS1
  • FADS3
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