GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

A genome-wide association study of a coronary artery disease risk variant.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
A5WWE7_DANRE ALDH2 ENSDARG00000037094 None Not determined 12
ALDH2 (3 of 4) ALDH2 ENSDARG00000090766 1 Not determined 12
aldh2a ALDH2 ENSDARG00000089924 None Not determined 12
aldh2b ALDH2 ENSDARG00000028087 None Not determined 12
C12orf51 (3 of 3) C12orf51 ENSDARG00000090715 None Not determined 9
C12orf51 (1 of 3) C12orf51 ENSDARG00000079151 5 Not determined 9
flt1 FLT1 ENSDARG00000019371 8 Normal 2
LOC100330423 C12orf51 ENSDARG00000003682 4 Not determined 9
myl2 MYL2 ENSDARG00000053424 None Not determined 4
MYL2 (2 of 2) MYL2 ENSDARG00000043349 None Not determined 4
sb:cb1008 CUX2 ENSDARG00000086559 2 Not determined 2
si:ch211-218i18.2 CUX2 ENSDARG00000086345 None Not determined 2
zgc:85777 ACAD10 ENSDARG00000027009 2 Normal 3

The following reported genes could not be linked automatically to a zebrafish gene:

  • CDKN2A/2B
  • RPL6-PTPN11
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