GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
alg14 ALG14 ENSDARG00000039671 None Not determined 2
CAMTA1 CAMTA1 ENSDARG00000007824 6 Not determined 2
chmp4b CHMP4B ENSDARG00000007323 1 Not determined 1
cnn3a CNN3 ENSDARG00000008359 None Not determined 1
cnn3b CNN3 ENSDARG00000029856 2 Not determined 1
D3J0E8_DANRE GCNT4 ENSDARG00000086781 None Not determined 1
fads2 FADS2 ENSDARG00000019532 None Not determined 15
fen1 FEN1 ENSDARG00000011404 4 Not determined 4
gcnt4 GCNT4 ENSDARG00000035198 None Not determined 1
GRID1 (2 of 2) GRID1 ENSDARG00000044161 3 Not determined 4
hif1an HIF1AN ENSDARG00000031915 2 Not determined 1
LOC100150238 PPT2 ENSDARG00000068846 None Not determined 2
LOC100151589 GRID1 ENSDARG00000070511 1 Not determined 4
LOC100331248 RAB3IL1 ENSDARG00000007711 1 Not determined 2
LOC100333044 GCKR ENSDARG00000086620 None Not determined 39
LOC793756 GRID1 ENSDARG00000074583 4 Normal 4
LOC797302 GCNT4 ENSDARG00000044755 2 Not determined 1
MCTP2 (1 of 2) MCTP2 ENSDARG00000073970 2 Not determined 5
ndufb8 NDUFB8 ENSDARG00000010113 None Not determined 1
pkd2l1 PKD2L1 ENSDARG00000022503 3 Not determined 3
ppt2 PPT2 ENSDARG00000070883 4 Normal 2
sec31b SEC31B ENSDARG00000002916 4 Not determined 1
si:ch211-214d15.1 MCTP2 ENSDARG00000001414 3 Not determined 5
si:ch211-245h14.2 ZNF512 ENSDARG00000041910 5 Not determined 2
si:ch211-251b21.1 GRID1 ENSDARG00000007275 1 Not determined 4
si:ch211-32g22.1 GCNT4 ENSDARG00000077550 None Not determined 1
si:dkey-10f21.4 TMEM56 ENSDARG00000057743 None Not determined 1
tmem56a TMEM56 ENSDARG00000056960 None Not determined 1
tmem56b TMEM56 ENSDARG00000043595 1 Not determined 1
wnt8b WNT8B ENSDARG00000006911 1 Not determined 1
zgc:172183 C11orf9 ENSDARG00000078676 2 Not determined 3
zgc:55413 PPT2 ENSDARG00000014208 4 Not determined 2
zgc:55621 PPT2 ENSDARG00000010782 2 Not determined 2
zgc:56112 CHMP4B ENSDARG00000016255 1 Not determined 1
zgc:66024 PPT2 ENSDARG00000068840 None Not determined 2
zgc:73269 C11orf10 ENSDARG00000078785 None Not determined 4
zgc:77118 PPT2 ENSDARG00000093176 1 Not determined 2

The following reported genes could not be linked automatically to a zebrafish gene:

  • ABCA4
  • AGPAT1
  • ANXA4
  • B4GALT5
  • C10orf71
  • C11orf0
  • C14orf45
  • C2orf16
  • C6orf167
  • CNN3
  • CSNK1A1L
  • EGFL8
  • FADS1
  • FADS1
  • FADS1
  • FADS3
  • FADS3
  • FAM13C1
  • FEN1
  • FLJ1111
  • FLJ40235
  • GCKR
  • GPR61
  • GRIK2
  • HS6ST1
  • IL5RA
  • KCNJ16
  • LOC729355
  • LPGAT1
  • LSM5
  • LYZL1
  • MY03B
  • NAP5
  • NUFIP1
  • PLEKHA6
  • PLXNA4
  • PMP22CD
  • PTPRD
  • RWDD3
  • RWDD3
  • SCD
  • SCD
  • SLC15A4
  • TMEM56
  • XAB1
  • XRCC2
  • ZNF659
Short-link