GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese population.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
anxa3a ANXA3 ENSDARG00000009196 2 Not determined 2
anxa3b ANXA3 ENSDARG00000044254 None Not determined 2
ARAP1 (3 of 3) ARAP1 ENSDARG00000087470 None Not determined 3
ARAP1 (1 of 3) ARAP1 ENSDARG00000091634 None Not determined 3
ARID5B ARID5B ENSDARG00000037196 2 Not determined 7
fli1a FLI1 ENSDARG00000054632 1 Not determined 3
fli1b FLI1 ENSDARG00000040080 1 Not determined 3
GCH1 GCH1 ENSDARG00000070453 1 Not determined 2
gch2 GCH1 ENSDARG00000013340 None Not determined 2
irf8 IRF8 ENSDARG00000056407 None Not determined 9
LOC100332468 PDE2A ENSDARG00000079064 None Not determined 2
LOC100332526 ARAP1 ENSDARG00000086356 1 Not determined 3
LOC558930 B3GNT2 ENSDARG00000089094 1 Not determined 2
PDE2A (2 of 2) PDE2A ENSDARG00000091508 None Not determined 2
PLD4 PLD4 ENSDARG00000075770 1 Not determined 1
prkcha PRKCH ENSDARG00000018382 1 Not determined 1
prkchb PRKCH ENSDARG00000043243 3 Not determined 1
ptpn2a PTPN2 ENSDARG00000016481 4 Not determined 13
ptpn2b PTPN2 ENSDARG00000035986 2 Not determined 13
si:ch211-135f11.1 ARAP1 ENSDARG00000062221 None Not determined 3
si:ch211-213b8.3 B3GNT2 ENSDARG00000052376 1 Not determined 2
si:dkey-175m17.6 B3GNT2 ENSDARG00000088601 1 Not determined 2
zgc:113947 B3GNT2 ENSDARG00000091902 None Not determined 2
zgc:158276 NFKBIE ENSDARG00000068367 None Not determined 2
zgc:158706 ARID5B ENSDARG00000069988 None Not determined 7
zgc:77151 ARID5B ENSDARG00000054307 1 Not determined 7

The following reported genes could not be linked automatically to a zebrafish gene:

  • CD83
  • CSF2
  • ETS1
  • PRKCB1
  • ZNF774
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