GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
eomesa EOMES ENSDARG00000006640 1 Not determined 2
eomesb EOMES ENSDARG00000019428 3 Not determined 2
FBXO48 FBXO48 ENSDARG00000086184 None Not determined 1
il12ba IL12B ENSDARG00000033727 2 Not determined 14
ildr1 ILDR1 ENSDARG00000040910 None Not determined 1
kpnb1 KPNB1 ENSDARG00000008680 None Not determined 1
LOC100001799 IL12B ENSDARG00000069504 1 Not determined 14
LOC100332780 ZMIZ1 ENSDARG00000076477 3 Not determined 10
LOC559568 TBKBP1 ENSDARG00000061473 3 Not determined 2
LOC563218 C16orf75 ENSDARG00000074444 None Not determined 2
mhc2dab HLA-DRB1 ENSDARG00000079105 None Not determined 35
NP_001091732.1 HLA-DRB1 ENSDARG00000071168 1 Not determined 35
plek PLEK ENSDARG00000017298 1 Not determined 4
si:busm1-104n07.3 HLA-DRB1 ENSDARG00000074510 1 Normal 35
si:busm1-160c18.3 HLA-DRB1 ENSDARG00000053738 None Not determined 35
si:busm1-160c18.3 HLA-DRB1 ENSDARG00000093706 None Not determined 35
si:busm1-194e12.12 HLA-DRB1 ENSDARG00000055447 None Not determined 35
si:busm1-228j01.4 HLA-DRB1 ENSDARG00000088872 2 Not determined 35
si:busm1-228j01.6 HLA-DRB1 ENSDARG00000041705 1 Not determined 35
si:ch211-213n8.3 IL12B ENSDARG00000054542 1 Not determined 14
si:dkeyp-192m14.7 EPS15L1 ENSDARG00000042670 4 Not determined 2
si:zfos-2070c2.3 HLA-DRB1 ENSDARG00000076307 None Not determined 35
stat3 STAT3 ENSDARG00000022712 5 Not determined 7
tagap TAGAP ENSDARG00000043475 4 Not determined 7
tbx21 TBX21 ENSDARG00000004473 None Not determined 1
wu:fd58b11 HLA-DRB1 ENSDARG00000054921 None Not determined 35
zgc:113068 THADA ENSDARG00000053082 2 Not determined 10
zgc:153067 HLA-DRB1 ENSDARG00000056330 2 Not determined 35
zgc:64227 ILDR1 ENSDARG00000090704 None Not determined 1
zgc:77799 TAGAP ENSDARG00000002353 None Not determined 7
zmiz1 ZMIZ1 ENSDARG00000074502 10 Not determined 10

The following reported genes could not be linked automatically to a zebrafish gene:

  • C2orf13
  • CD40
  • CD58
  • CD86
  • HLA-B
  • IL2RA
  • MLANA
  • PRM1
  • PRM2
  • PRM3
  • TNP2
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