GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Eight genetic loci associated with variation in lipoprotein-associated phospholipase A2 mass and activity and coronary heart disease: meta-analysis of genome-wide association studies from five community-based studies.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
celsr1a CELSR2 ENSDARG00000069185 8 Not determined 17
CELSR2 CELSR2 ENSDARG00000088231 4 Not determined 17
celsr2l CELSR2 ENSDARG00000019726 2 Not determined 17
cetp CETP ENSDARG00000030872 2 Not determined 27
ldlr LDLR ENSDARG00000029476 3 Not determined 15
LDLR (2 of 2) LDLR ENSDARG00000089730 None Not determined 15
si:dkey-258f14.3 LDLR ENSDARG00000075974 None Not determined 15
si:dkey-30k22.7 CELSR2 ENSDARG00000037286 4 Not determined 17
zgc:77563 PLA2G7 ENSDARG00000003584 1 Not determined 3
znf259 ZNF259 ENSDARG00000043542 2 Not determined 11

The following reported genes could not be linked automatically to a zebrafish gene:

  • APOC1
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