GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

A genome-wide meta-analysis of six type 1 diabetes cohorts identifies multiple associated loci.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
A1A5U5_DANRE DLL1 ENSDARG00000077129 1 Not determined 1
adcy3 ADCY3 ENSDARG00000017437 3 Not determined 6
ADCY3 (1 of 2) ADCY3 ENSDARG00000077145 None Not determined 6
dla DLL1 ENSDARG00000010791 1 Not determined 1
dld DLL1 ENSDARG00000020219 3 Not determined 1
dnajc27 DNAJC27 ENSDARG00000070916 None Not determined 4
dnmt6 DNMT3A ENSDARG00000015566 2 Not determined 3
dnmt8 DNMT3A ENSDARG00000005394 5 Normal 3
efr3ba EFR3B ENSDARG00000033516 1 Not determined 1
efr3bb EFR3B ENSDARG00000069318 2 Not determined 1
fosl2 FOSL2 ENSDARG00000040623 None Not determined 2
lmo7a LMO7 ENSDARG00000004930 9 Not determined 1
lmo7b LMO7 ENSDARG00000053535 8 Not determined 1
phf10 PHF10 ENSDARG00000070084 3 Not determined 1
pomca POMC ENSDARG00000043135 None Not determined 4
pomcb POMC ENSDARG00000069307 1 Not determined 4
psmb1 PSMB1 ENSDARG00000009640 1 Not determined 1
si:ch211-59d15.4 FOSL2 ENSDARG00000092174 None Not determined 2
si:dkey-273e13.4 WDR27 ENSDARG00000077977 2 Not determined 1
si:dkey-34f16.5 C2orf79 ENSDARG00000016122 1 Normal 1
tbp TBP ENSDARG00000014994 None Not determined 1
zgc:101006 FAM120B ENSDARG00000030804 2 Normal 1
zgc:123251 WDR27 ENSDARG00000053386 5 Not determined 1
zgc:171667 CENPO ENSDARG00000075619 2 Not determined 1
zgc:77929 C6orf120 ENSDARG00000017337 None Not determined 1

The following reported genes could not be linked automatically to a zebrafish gene:

  • 3NCOA1
  • C6orf208
  • LOC100128081
  • LOC154449
  • PCD2
  • TCTE3
  • TNFRSF11B
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