(GWAS data used on the Zebrafish Mutation Project Web site comes from

Identification of novel genetic markers associated with clinical phenotypes of systemic sclerosis through a genome-wide association strategy.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
cd247l CD247 ENSDARG00000077240 1 Not determined 6
esyt1a ESYT1 ENSDARG00000034714 5 Not determined 1
esyt1b ESYT1 ENSDARG00000014239 7 Not determined 1
grb10a GRB10 ENSDARG00000002013 3 Normal 3
irf5 IRF5 ENSDARG00000045681 None Not determined 14
irf8 IRF8 ENSDARG00000056407 None Not determined 9
mhc2dab HLA-DRB1 ENSDARG00000079105 None Not determined 35
mhc2dab HLA-DQB1 ENSDARG00000079105 None Not determined 24
mhc2dab HLA-DPB1 ENSDARG00000079105 None Not determined 7
NP_001091732.1 HLA-DPB1 ENSDARG00000071168 1 Not determined 7
NP_001091732.1 HLA-DRB1 ENSDARG00000071168 1 Not determined 35
NP_001091732.1 HLA-DQB1 ENSDARG00000071168 1 Not determined 24
si:busm1-104n07.3 HLA-DPB1 ENSDARG00000074510 1 Normal 7
si:busm1-104n07.3 HLA-DRB1 ENSDARG00000074510 1 Normal 35
si:busm1-104n07.3 HLA-DQB1 ENSDARG00000074510 1 Normal 24
si:busm1-160c18.1 HLA-DQA1 ENSDARG00000053739 2 Not determined 27
si:busm1-160c18.1 HLA-DRA ENSDARG00000053739 2 Not determined 21
si:busm1-160c18.1 HLA-DPA1 ENSDARG00000053739 2 Not determined 4
si:busm1-160c18.3 HLA-DPB1 ENSDARG00000053738 None Not determined 7
si:busm1-160c18.3 HLA-DRB1 ENSDARG00000053738 None Not determined 35
si:busm1-160c18.3 HLA-DQB1 ENSDARG00000053738 None Not determined 24
si:busm1-160c18.3 HLA-DPB1 ENSDARG00000093706 None Not determined 7
si:busm1-160c18.3 HLA-DRB1 ENSDARG00000093706 None Not determined 35
si:busm1-160c18.3 HLA-DQB1 ENSDARG00000093706 None Not determined 24
si:busm1-194e12.11 HLA-DRA ENSDARG00000055441 1 Not determined 21
si:busm1-194e12.11 HLA-DPA1 ENSDARG00000055441 1 Not determined 4
si:busm1-194e12.11 HLA-DQA1 ENSDARG00000055441 1 Not determined 27
si:busm1-194e12.12 HLA-DPB1 ENSDARG00000055447 None Not determined 7
si:busm1-194e12.12 HLA-DRB1 ENSDARG00000055447 None Not determined 35
si:busm1-194e12.12 HLA-DQB1 ENSDARG00000055447 None Not determined 24
si:busm1-228j01.3 HLA-DRA ENSDARG00000086294 2 Not determined 21
si:busm1-228j01.3 HLA-DPA1 ENSDARG00000086294 2 Not determined 4
si:busm1-228j01.3 HLA-DQA1 ENSDARG00000086294 2 Not determined 27
si:busm1-228j01.4 HLA-DPB1 ENSDARG00000088872 2 Not determined 7
si:busm1-228j01.4 HLA-DRB1 ENSDARG00000088872 2 Not determined 35
si:busm1-228j01.4 HLA-DQB1 ENSDARG00000088872 2 Not determined 24
si:busm1-228j01.5 HLA-DRA ENSDARG00000079593 3 Not determined 21
si:busm1-228j01.5 HLA-DPA1 ENSDARG00000079593 3 Not determined 4
si:busm1-228j01.5 HLA-DQA1 ENSDARG00000079593 3 Not determined 27
si:busm1-228j01.6 HLA-DRB1 ENSDARG00000041705 1 Not determined 35
si:busm1-228j01.6 HLA-DQB1 ENSDARG00000041705 1 Not determined 24
si:busm1-228j01.6 HLA-DPB1 ENSDARG00000041705 1 Not determined 7
si:ch1073-403i13.1 HLA-DRA ENSDARG00000001832 None Not determined 21
si:ch1073-403i13.1 HLA-DPA1 ENSDARG00000001832 None Not determined 4
si:ch1073-403i13.1 HLA-DQA1 ENSDARG00000001832 None Not determined 27
si:ch211-149m3.3 GRB10 ENSDARG00000035308 8 Not determined 3
si:ch73-211l2.3 HLA-DRA ENSDARG00000075932 1 Not determined 21
si:ch73-211l2.3 HLA-DPA1 ENSDARG00000075932 1 Not determined 4
si:ch73-211l2.3 HLA-DQA1 ENSDARG00000075932 1 Not determined 27
si:dkeyp-2h4.2 HLA-DRA ENSDARG00000031745 None Not determined 21
si:dkeyp-2h4.2 HLA-DPA1 ENSDARG00000031745 None Not determined 4
si:dkeyp-2h4.2 HLA-DQA1 ENSDARG00000031745 None Not determined 27
si:zfos-2070c2.1 HLA-DRA ENSDARG00000070206 None Not determined 21
si:zfos-2070c2.1 HLA-DPA1 ENSDARG00000070206 None Not determined 4
si:zfos-2070c2.1 HLA-DQA1 ENSDARG00000070206 None Not determined 27
si:zfos-2070c2.3 HLA-DPB1 ENSDARG00000076307 None Not determined 7
si:zfos-2070c2.3 HLA-DRB1 ENSDARG00000076307 None Not determined 35
si:zfos-2070c2.3 HLA-DQB1 ENSDARG00000076307 None Not determined 24
si:zfos-367g9.1 HLA-DRA ENSDARG00000074816 1 Not determined 21
si:zfos-367g9.1 HLA-DPA1 ENSDARG00000074816 1 Not determined 4
si:zfos-367g9.1 HLA-DQA1 ENSDARG00000074816 1 Not determined 27
sox5 SOX5 ENSDARG00000011582 3 Not determined 6
stat4 STAT4 ENSDARG00000028731 3 Not determined 19
wu:fd58b11 HLA-DPB1 ENSDARG00000054921 None Not determined 7
wu:fd58b11 HLA-DRB1 ENSDARG00000054921 None Not determined 35
wu:fd58b11 HLA-DQB1 ENSDARG00000054921 None Not determined 24
zgc:123107 HLA-DQA1 ENSDARG00000020286 None Not determined 27
zgc:123107 HLA-DRA ENSDARG00000020286 None Not determined 21
zgc:123107 HLA-DPA1 ENSDARG00000020286 None Not determined 4
zgc:153067 HLA-DRB1 ENSDARG00000056330 2 Not determined 35
zgc:153067 HLA-DQB1 ENSDARG00000056330 2 Not determined 24
zgc:153067 HLA-DPB1 ENSDARG00000056330 2 Not determined 7

The following reported genes could not be linked automatically to a zebrafish gene:

  • NOTCH4
  • NOTCH4
  • RPL41