GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Genome-wide scan identifies TNIP1, PSORS1C1, and RHOB as novel risk loci for systemic sclerosis.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
cd247l CD247 ENSDARG00000077240 1 Not determined 6
irf5 IRF5 ENSDARG00000045681 None Not determined 14
stat4 STAT4 ENSDARG00000028731 3 Not determined 19
tnip1 TNIP1 ENSDARG00000015653 2 Not determined 6
tnpo3 TNPO3 ENSDARG00000045680 4 Not determined 7

The following reported genes could not be linked automatically to a zebrafish gene:

  • DQB1
  • HLA
  • PSORS1C1
  • RHOB
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