GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Two-marker association tests yield new disease associations for coronary artery disease and hypertension.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
cdkn2b CDKN2A ENSDARG00000037262 2 Not determined 25
cdkn2b CDKN2B ENSDARG00000037262 2 Not determined 30
gpr39 GPR39 ENSDARG00000042939 1 Not determined 1
hfe2 HFE2 ENSDARG00000030494 None Not determined 1
hsp90b1 HSP90B1 ENSDARG00000003570 2 Not determined 1
myo6a MYO6 ENSDARG00000044016 5 Normal 1
myo6b MYO6 ENSDARG00000042141 3 Not determined 1
xrcc4 XRCC4 ENSDARG00000010732 3 Not determined 1
zfat ZFAT ENSDARG00000077987 3 Not determined 2

The following reported genes could not be linked automatically to a zebrafish gene:

  • AN06
  • MACROD2
  • NOV
  • RANBP3L
  • STK32B
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