GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
A5PMT7_DANRE LAMC2 ENSDARG00000068288 1 Not determined 2
bltk BLK ENSDARG00000007783 2 Not determined 11
COL25A1 (2 of 2) COL25A1 ENSDARG00000022620 None Not determined 1
COL25A1 (1 of 2) COL25A1 ENSDARG00000068218 2 Not determined 1
irf5 IRF5 ENSDARG00000045681 None Not determined 14
ITGAM ITGAM ENSDARG00000002956 2 Not determined 5
NAALADL2 NAALADL2 ENSDARG00000086489 2 Not determined 4
si:busm1-160c18.1 HLA-DQA2 ENSDARG00000053739 2 Not determined 17
si:busm1-160c18.1 HLA-DQA1 ENSDARG00000053739 2 Not determined 27
si:busm1-194e12.11 HLA-DQA1 ENSDARG00000055441 1 Not determined 27
si:busm1-194e12.11 HLA-DQA2 ENSDARG00000055441 1 Not determined 17
si:busm1-228j01.3 HLA-DQA1 ENSDARG00000086294 2 Not determined 27
si:busm1-228j01.3 HLA-DQA2 ENSDARG00000086294 2 Not determined 17
si:busm1-228j01.5 HLA-DQA1 ENSDARG00000079593 3 Not determined 27
si:busm1-228j01.5 HLA-DQA2 ENSDARG00000079593 3 Not determined 17
si:ch1073-403i13.1 HLA-DQA2 ENSDARG00000001832 None Not determined 17
si:ch1073-403i13.1 HLA-DQA1 ENSDARG00000001832 None Not determined 27
si:ch211-232m8.6 PTTG1 ENSDARG00000075421 None Not determined 2
si:ch73-116b16.2 SLC1A7 ENSDARG00000026248 None Not determined 2
si:ch73-211l2.3 HLA-DQA1 ENSDARG00000075932 1 Not determined 27
si:ch73-211l2.3 HLA-DQA2 ENSDARG00000075932 1 Not determined 17
si:dkey-192o1.2 PTTG1 ENSDARG00000090991 None Not determined 2
si:dkey-229d2.2 TMC2 ENSDARG00000030311 2 Not determined 2
si:dkey-267i17.6 TMC2 ENSDARG00000033104 2 Not determined 2
si:dkey-27a13.1 COL25A1 ENSDARG00000093421 2 Not determined 1
si:dkeyp-2h4.2 HLA-DQA1 ENSDARG00000031745 None Not determined 27
si:dkeyp-2h4.2 HLA-DQA2 ENSDARG00000031745 None Not determined 17
si:zfos-2070c2.1 HLA-DQA1 ENSDARG00000070206 None Not determined 27
si:zfos-2070c2.1 HLA-DQA2 ENSDARG00000070206 None Not determined 17
si:zfos-367g9.1 HLA-DQA1 ENSDARG00000074816 1 Not determined 27
si:zfos-367g9.1 HLA-DQA2 ENSDARG00000074816 1 Not determined 17
slc1a7a SLC1A7 ENSDARG00000034940 1 Not determined 2
slc1a8a SLC1A7 ENSDARG00000034628 2 Not determined 2
slc1a8b SLC1A7 ENSDARG00000032465 None Not determined 2
stat4 STAT4 ENSDARG00000028731 3 Not determined 19
tnxb TNXB ENSDARG00000001760 5 Not determined 4
ube2l3a UBE2L3 ENSDARG00000019188 None Not determined 8
ube2l3b UBE2L3 ENSDARG00000027141 1 Not determined 8
zgc:123107 HLA-DQA1 ENSDARG00000020286 None Not determined 27
zgc:123107 HLA-DQA2 ENSDARG00000020286 None Not determined 17

The following reported genes could not be linked automatically to a zebrafish gene:

  • C6orf10
  • HLA-DR3
  • KIAA1542
  • NOTCH4
  • OR4A15
  • RPL7AP59
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