GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Genome-wide association study for C-reactive protein levels identified pleiotropic associations in the IL6 locus.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
hnf1a HNF1A ENSDARG00000009470 None Not determined 21
si:ch211-234p6.10 CRP ENSDARG00000056498 None Not determined 13
si:ch211-234p6.12 CRP ENSDARG00000042613 None Not determined 13
si:ch211-234p6.13 CRP ENSDARG00000056462 None Not determined 13
si:ch211-234p6.14 CRP ENSDARG00000071454 2 Not determined 13
si:ch211-234p6.7 CRP ENSDARG00000071456 None Not determined 13
si:ch211-234p6.8 CRP ENSDARG00000071457 None Not determined 13
si:ch211-234p6.9 CRP ENSDARG00000095730 None Not determined 13
si:ch211-270n8.1 CRP ENSDARG00000045089 None Not determined 13
zgc:101049 CRP ENSDARG00000071051 1 Not determined 13

The following reported genes could not be linked automatically to a zebrafish gene:

  • APOE-CI-CII cluster
  • IL6
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