GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
ifih1 IFIH1 ENSDARG00000018553 1 Not determined 7
il12ba IL12B ENSDARG00000033727 2 Not determined 14
LOC100001799 IL12B ENSDARG00000069504 1 Not determined 14
nfkbiaa NFKBIA ENSDARG00000005481 None Not determined 2
nfkbiab NFKBIA ENSDARG00000007693 1 Not determined 2
rel REL ENSDARG00000055276 4 Not determined 10
si:ch211-213n8.3 IL12B ENSDARG00000054542 1 Not determined 14
si:ch211-274c22.6 TNFAIP3 ENSDARG00000027777 5 Not determined 11
si:dkey-24n17.6 ERAP1 ENSDARG00000013024 2 Not determined 7
TRAF3IP2 TRAF3IP2 ENSDARG00000087515 None Not determined 4
TYK2 TYK2 ENSDARG00000020326 4 Not determined 6
zgc:56194 ERAP1 ENSDARG00000021859 1 Not determined 7

The following reported genes could not be linked automatically to a zebrafish gene:

  • HLA-C
  • IL23A
  • IL23R
  • IL28RA
  • LCE3D
  • ZNF313
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