GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
ABCB11 ABCB11 ENSDARG00000070078 2 Not determined 6
abcb11a ABCB11 ENSDARG00000011573 6 Not determined 6
fn3krp FN3K ENSDARG00000025086 None Not determined 1
gck GCK ENSDARG00000068006 1 Not determined 7
hk1 HK1 ENSDARG00000039452 3 Not determined 4
mhc1uba HFE ENSDARG00000075963 None Not determined 20
mhc1ze HFE ENSDARG00000074765 None Not determined 20
mhc1zel HFE ENSDARG00000092162 1 Not determined 20
MR1BB_DANRE MTNR1B ENSDARG00000086493 None Not determined 15
mtnr1ba MTNR1B ENSDARG00000053833 None Not determined 15
mtnr1bb MTNR1B ENSDARG00000086883 None Not determined 15
NP_919406.1 HFE ENSDARG00000086877 1 Not determined 20
Q8MHB3_DANRE HFE ENSDARG00000076734 None Not determined 20
Q8MHB6_DANRE HFE ENSDARG00000088022 1 Not determined 20
si:ch211-231a1.5 TMPRSS6 ENSDARG00000094087 None Not determined 14
si:ch211-287j19.6 HFE ENSDARG00000001470 2 Not determined 20
si:ch73-213j4.4 HFE ENSDARG00000092731 None Not determined 20
si:dkey-251i8.1 ATP11A ENSDARG00000008413 3 Not determined 1
tubgcp3 TUBGCP3 ENSDARG00000029133 None Not determined 1
zgc:136614 HFE ENSDARG00000069471 None Not determined 20
zgc:64115 HFE ENSDARG00000036588 4 Not determined 20

The following reported genes could not be linked automatically to a zebrafish gene:

  • ANK1
  • ANK1
  • G6PC2
Short-link