GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Variant of TYR and autoimmunity susceptibility loci in generalized vitiligo.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
BTNL2 BTNL2 ENSDARG00000093039 1 Not determined 18
lpp LPP ENSDARG00000023578 1 Not determined 10
ptpn22 PTPN22 ENSDARG00000075062 5 Not determined 17
rbm17 RBM17 ENSDARG00000031346 8 Not determined 1
rerea RERE ENSDARG00000077353 8 Not determined 4
rereb RERE ENSDARG00000075670 4 Not determined 4
si:busm1-160c18.1 HLA-DRA ENSDARG00000053739 2 Not determined 21
si:busm1-160c18.1 HLA-DQA1 ENSDARG00000053739 2 Not determined 27
si:busm1-194e12.11 HLA-DRA ENSDARG00000055441 1 Not determined 21
si:busm1-194e12.11 HLA-DQA1 ENSDARG00000055441 1 Not determined 27
si:busm1-228j01.3 HLA-DRA ENSDARG00000086294 2 Not determined 21
si:busm1-228j01.3 HLA-DQA1 ENSDARG00000086294 2 Not determined 27
si:busm1-228j01.5 HLA-DQA1 ENSDARG00000079593 3 Not determined 27
si:busm1-228j01.5 HLA-DRA ENSDARG00000079593 3 Not determined 21
si:ch1073-403i13.1 HLA-DRA ENSDARG00000001832 None Not determined 21
si:ch1073-403i13.1 HLA-DQA1 ENSDARG00000001832 None Not determined 27
si:ch73-211l2.3 HLA-DQA1 ENSDARG00000075932 1 Not determined 27
si:ch73-211l2.3 HLA-DRA ENSDARG00000075932 1 Not determined 21
si:dkeyp-2h4.2 HLA-DQA1 ENSDARG00000031745 None Not determined 27
si:dkeyp-2h4.2 HLA-DRA ENSDARG00000031745 None Not determined 21
si:zfos-2070c2.1 HLA-DRA ENSDARG00000070206 None Not determined 21
si:zfos-2070c2.1 HLA-DQA1 ENSDARG00000070206 None Not determined 27
si:zfos-367g9.1 HLA-DRA ENSDARG00000074816 1 Not determined 21
si:zfos-367g9.1 HLA-DQA1 ENSDARG00000074816 1 Not determined 27
tyr TYR ENSDARG00000039077 None Not determined 9
zgc:123107 HLA-DRA ENSDARG00000020286 None Not determined 21
zgc:123107 HLA-DQA1 ENSDARG00000020286 None Not determined 27

The following reported genes could not be linked automatically to a zebrafish gene:

  • C1QTNF6
  • GZMB
  • HCG9
  • HLA-A
  • IL2RA
  • PFKB3
  • UBASH3A
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