GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
adra2a ADRA2A ENSDARG00000040841 4 Not determined 3
cry-dash CRY2 ENSDARG00000002396 2 Not determined 3
cry3 CRY2 ENSDARG00000079444 None Not determined 3
cry4 CRY2 ENSDARG00000011890 1 Not determined 3
cry5 CRY2 ENSDARG00000019498 1 Not determined 3
DGKB DGKB ENSDARG00000027724 1 Not determined 4
gck GCK ENSDARG00000068006 1 Not determined 7
glis3 GLIS3 ENSDARG00000069726 5 Not determined 6
igf1 IGF1 ENSDARG00000094132 None Not determined 5
LOC100002134 SLC30A8 ENSDARG00000054584 1 Not determined 16
LOC100329739 CRY2 ENSDARG00000088549 2 Not determined 3
LOC100333044 GCKR ENSDARG00000086620 None Not determined 39
LOC100334818 SLC2A2 ENSDARG00000001937 1 Not determined 3
LOC560642 SLC30A8 ENSDARG00000057629 None Not determined 16
madd MADD ENSDARG00000003495 8 Not determined 4
MR1BB_DANRE MTNR1B ENSDARG00000086493 None Not determined 15
mtnr1ba MTNR1B ENSDARG00000053833 None Not determined 15
mtnr1bb MTNR1B ENSDARG00000086883 None Not determined 15
NP_001165056.1 ADCY5 ENSDARG00000091342 1 Not determined 7
NP_571861.2 CRY2 ENSDARG00000024049 None Not determined 3
prox1 PROX1 ENSDARG00000055158 2 Not determined 2
prox1b PROX1 ENSDARG00000088810 2 Not determined 2
slc2a2 SLC2A2 ENSDARG00000056196 None Not determined 3
tcf7l2 TCF7L2 ENSDARG00000004415 5 Not determined 23
tmem195 TMEM195 ENSDARG00000025595 4 Not determined 2
zgc:162595 C2CD4B ENSDARG00000061416 None Not determined 5

The following reported genes could not be linked automatically to a zebrafish gene:

  • FADS1
  • FADS1
  • G6PC2
  • G6PC2
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