GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Genome-wide association study identifies eight loci associated with blood pressure.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
arid3b ARID3B ENSDARG00000070474 1 Not determined 1
ARID5B ARID5B ENSDARG00000037196 2 Not determined 7
as3mt AS3MT ENSDARG00000027572 None Not determined 3
clcn6 CLCN6 ENSDARG00000032577 3 Not determined 2
cnnm2a CNNM2 ENSDARG00000061195 2 Not determined 9
cnnm2b CNNM2 ENSDARG00000078733 1 Not determined 9
cplx3a CPLX3 ENSDARG00000062508 None Not determined 3
cplx3b CPLX3 ENSDARG00000089486 None Not determined 3
CSK (2 of 2) CSK ENSDARG00000067996 None Not determined 4
cyp17a1 CYP17A1 ENSDARG00000033566 3 Not determined 7
cyp17a2 CYP17A1 ENSDARG00000053966 None Not determined 7
cyp1a CYP1A1 ENSDARG00000026039 1 Not determined 5
cyp1a CYP1A2 ENSDARG00000026039 1 Not determined 4
cyp1d1 CYP1A1 ENSDARG00000035569 None Not determined 5
cyp1d1 CYP1A2 ENSDARG00000035569 None Not determined 4
fgf5 FGF5 ENSDARG00000035377 1 Not determined 4
im:6894391 AGTRAP ENSDARG00000077082 1 Not determined 1
LOC794507 TMEM26 ENSDARG00000077979 1 Not determined 1
NP_001071067.1 CSK ENSDARG00000070805 1 Not determined 4
NP_001165054.1 CPLX3 ENSDARG00000091510 None Not determined 3
nt5c2a NT5C2 ENSDARG00000039399 3 Not determined 9
nt5c2b NT5C2 ENSDARG00000058231 2 Not determined 9
phb PHB ENSDARG00000057414 1 Not determined 1
plcd3a PLCD3 ENSDARG00000052957 4 Not determined 1
prdm8 PRDM8 ENSDARG00000025017 1 Not determined 1
prdm8b PRDM8 ENSDARG00000054683 2 Not determined 1
RHOBTB1 RHOBTB1 ENSDARG00000079468 1 Not determined 1
rhobtb2a RHOBTB1 ENSDARG00000016868 3 Not determined 1
rtkn2 RTKN2 ENSDARG00000053558 2 Not determined 3
SH2B3 (1 of 2) SH2B3 ENSDARG00000069958 None Not determined 19
si:ch211-113n10.6 ARID3B ENSDARG00000067729 None Not determined 1
si:dkey-163f12.11 TMEM26 ENSDARG00000094861 None Not determined 1
si:dkey-165i4.1 ATXN2 ENSDARG00000052897 5 Normal 10
si:dkeyp-100a1.4 MTHFR ENSDARG00000053087 None Not determined 4
si:dkeyp-1e8.2 SH2B3 ENSDARG00000093095 None Not determined 19
si:dkeyp-41f9.4 PRDM8 ENSDARG00000092269 None Not determined 1
si:dkeyp-94b4.3 PLCD3 ENSDARG00000079572 4 Not determined 1
zgc:153372 AS3MT ENSDARG00000068967 2 Not determined 3
zgc:158706 ARID5B ENSDARG00000069988 None Not determined 7
zgc:162976 HEXIM2 ENSDARG00000036482 2 Not determined 1
zgc:162976 HEXIM1 ENSDARG00000036482 2 Not determined 1
zgc:172258 TMEM26 ENSDARG00000014682 2 Not determined 1
zgc:77151 ARID5B ENSDARG00000054307 1 Not determined 7
zgc:85611 ACBD4 ENSDARG00000027070 None Not determined 3
znf652 ZNF652 ENSDARG00000062302 1 Not determined 5

The following reported genes could not be linked automatically to a zebrafish gene:

  • c10orf107
  • c4orf22
  • LMAN1L
  • MDS1
  • NPPA
  • NPPB
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