GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Variants in TF and HFE explain approximately 40% of genetic variation in serum-transferrin levels.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
ARSB ARSB ENSDARG00000093887 None Not determined 2
BTNL2 BTN1A1 ENSDARG00000093039 1 Not determined 1
ghra GHR ENSDARG00000054771 2 Not determined 2
ghrb GHR ENSDARG00000007671 None Not determined 2
mhc1uba HFE ENSDARG00000075963 None Not determined 20
mhc1ze HFE ENSDARG00000074765 None Not determined 20
mhc1zel HFE ENSDARG00000092162 1 Not determined 20
NP_919406.1 HFE ENSDARG00000086877 1 Not determined 20
Q8MHB3_DANRE HFE ENSDARG00000076734 None Not determined 20
Q8MHB6_DANRE HFE ENSDARG00000088022 1 Not determined 20
si:ch1073-210b3.2 LRRC16A ENSDARG00000077661 1 Not determined 3
si:ch211-231a1.5 TMPRSS6 ENSDARG00000094087 None Not determined 14
si:ch211-243k12.1 LUZP2 ENSDARG00000068247 1 Not determined 5
si:ch211-287j19.6 HFE ENSDARG00000001470 2 Not determined 20
si:ch73-213j4.4 HFE ENSDARG00000092731 None Not determined 20
si:rp71-68n21.9 KLHL13 ENSDARG00000067751 1 Not determined 1
tfa TF ENSDARG00000016771 6 Not determined 5
topbp1 TOPBP1 ENSDARG00000059322 1 Not determined 1
wtap WTAP ENSDARG00000042642 1 Not determined 1
zgc:100843 SCGN ENSDARG00000058732 2 Not determined 2
zgc:136614 HFE ENSDARG00000069471 None Not determined 20
zgc:162040 RSPO3 ENSDARG00000070081 1 Not determined 7
zgc:163008 KLHL13 ENSDARG00000086463 3 Not determined 1
zgc:172271 TF ENSDARG00000013240 2 Not determined 5
zgc:64115 HFE ENSDARG00000036588 4 Not determined 20

The following reported genes could not be linked automatically to a zebrafish gene:

  • HIST1H2BJ
  • LRRC16
  • LRRC16
  • Q4KMW4
  • Q6ZNG6
  • Q6ZUR9
  • SLC17A1
  • TRIM38
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