GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
atg16l1 ATG16L1 ENSDARG00000057430 None Not determined 8
BSN (2 of 2) BSN ENSDARG00000079822 23 Not determined 4
BSN (1 of 2) BSN ENSDARG00000079161 11 Not determined 4
cdkal1 CDKAL1 ENSDARG00000022122 2 Not determined 23
cdkn2b CDKN2B ENSDARG00000037262 2 Not determined 30
cdkn2b CDKN2A ENSDARG00000037262 2 Not determined 25
chrm3a CHRM3 ENSDARG00000071091 1 Not determined 4
dctn5 DCTN5 ENSDARG00000003573 None Not determined 1
erbb3a ERBB3 ENSDARG00000006202 1 Not determined 8
erbb3b ERBB3 ENSDARG00000036993 7 Not determined 8
fto FTO ENSDARG00000044216 3 Not determined 32
irgf1 IRGM ENSDARG00000070774 3 Not determined 5
irgf2 IRGM ENSDARG00000092249 1 Not determined 5
irgf3 IRGM ENSDARG00000062820 None Not determined 5
irgq2 IRGM ENSDARG00000068657 None Not determined 5
LOC100149598 CHRM3 ENSDARG00000071298 2 Not determined 4
LOC794003 ZP4 ENSDARG00000073976 5 Not determined 2
mhc2dab HLA-DRB1 ENSDARG00000079105 None Not determined 35
ndufab1 NDUFAB1 ENSDARG00000014915 None Not determined 1
nkx2.3 NKX2-3 ENSDARG00000039095 None Not determined 10
nkx2.7 NKX2-3 ENSDARG00000021232 1 1 phenotype 10
nod2 NOD2 ENSDARG00000010756 3 Not determined 10
NP_001091732.1 HLA-DRB1 ENSDARG00000071168 1 Not determined 35
NP_694512.1 MST1 ENSDARG00000031855 2 Not determined 9
palb2 PALB2 ENSDARG00000076716 4 Not determined 1
ptpn11a PTPN11 ENSDARG00000020334 2 Not determined 8
ptpn22 PTPN22 ENSDARG00000075062 5 Not determined 17
ptpn2a PTPN2 ENSDARG00000016481 4 Not determined 13
ptpn2b PTPN2 ENSDARG00000035986 2 Not determined 13
RYR2 (1 of 3) RYR2 ENSDARG00000056058 1 Not determined 5
ryr2a RYR2 ENSDARG00000079171 1 Not determined 5
ryr2b RYR2 ENSDARG00000003706 1 Not determined 5
SH2B3 (1 of 2) SH2B3 ENSDARG00000069958 None Not determined 19
si:busm1-104n07.3 HLA-DRB1 ENSDARG00000074510 1 Normal 35
si:busm1-160c18.3 HLA-DRB1 ENSDARG00000053738 None Not determined 35
si:busm1-160c18.3 HLA-DRB1 ENSDARG00000093706 None Not determined 35
si:busm1-194e12.12 HLA-DRB1 ENSDARG00000055447 None Not determined 35
si:busm1-228j01.4 HLA-DRB1 ENSDARG00000088872 2 Not determined 35
si:busm1-228j01.6 HLA-DRB1 ENSDARG00000041705 1 Not determined 35
si:ch73-233m11.2 NOD2 ENSDARG00000091859 None Not determined 10
si:dkey-108d22.4 BSN ENSDARG00000063299 14 Normal 4
si:dkey-266j7.1 BSN ENSDARG00000012482 16 Not determined 4
si:dkeyp-1e8.2 SH2B3 ENSDARG00000093095 None Not determined 19
si:zfos-2070c2.3 HLA-DRB1 ENSDARG00000076307 None Not determined 35
tcf7l2 TCF7L2 ENSDARG00000004415 5 Not determined 23
wu:fd58b11 HLA-DRB1 ENSDARG00000054921 None Not determined 35
zgc:153067 HLA-DRB1 ENSDARG00000056330 2 Not determined 35
zgc:162228 TRAFD1 ENSDARG00000075123 None Not determined 2
zgc:92607 NDUFAB1 ENSDARG00000058463 None Not determined 1
zp2 ZP4 ENSDARG00000086352 1 Not determined 2
zp2 ZP4 ENSDARG00000089966 None Not determined 2
zp2.2 ZP4 ENSDARG00000091737 None Not determined 2
zp2.3 ZP4 ENSDARG00000090237 None Not determined 2
zp2.5 ZP4 ENSDARG00000086522 None Not determined 2
zp2.6 ZP4 ENSDARG00000091409 None Not determined 2
zp2l1 ZP4 ENSDARG00000055415 1 Not determined 2
zp2l2 ZP4 ENSDARG00000004898 None Not determined 2

The following reported genes could not be linked automatically to a zebrafish gene:

  • IL23R
  • KIAA0350
  • LNK
  • MHC
  • MHC
Short-link