GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
il12ba IL12B ENSDARG00000033727 2 Not determined 14
irgf1 IRGM ENSDARG00000070774 3 Not determined 5
irgf2 IRGM ENSDARG00000092249 1 Not determined 5
irgf3 IRGM ENSDARG00000062820 None Not determined 5
irgq2 IRGM ENSDARG00000068657 None Not determined 5
LOC100001799 IL12B ENSDARG00000069504 1 Not determined 14
nkx2.3 NKX2-3 ENSDARG00000039095 None Not determined 10
nkx2.7 NKX2-3 ENSDARG00000021232 1 1 phenotype 10
NP_694512.1 MST1 ENSDARG00000031855 2 Not determined 9
ptpn2a PTPN2 ENSDARG00000016481 4 Not determined 13
ptpn2b PTPN2 ENSDARG00000035986 2 Not determined 13
si:ch211-213n8.3 IL12B ENSDARG00000054542 1 Not determined 14
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