Mouse Genome Engineering | Model Pipelines

Mouse Genome Engineering | Model Pipelines

Mouse Genome Engineering

Our Research and Approach

Model Pipelines are headed by Ramiro Ramirez-Solis and produce and characterise knock-out mice for large-scale research projects, including the Sanger Mouse Genetics Project, National Institutes of Health KOMP2, EUCOMMTools, and the Infrafrontier projects.

Mouse Pipelines includes the following teams:

  • Mouse Genome Engineering
  • Mouse Transgenic Technologies
  • Mouse Molecular Technologies
  • Mouse Phenotyping
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Dr Ramiro Ramirez-Solis, PhD
Group Leader

I work with a large team of superb scientists to generate mutant mouse strains carrying alleles of biomedical importance. Our work includes design of the mutation, mutagenesis of mouse ES cells, CRISPR mutagenesis, transgenic technologies to transfer the allele into the germline, molecular analysis and genotyping, colony management, cryopreservation, phenotypic analysis, and strain distribution.

Partners and Funders

Internal Partners