25 species revealed for 25 Genomes Project
BioBright, Sanger Institute aim to cut drug-development time
BioBright, a firm dedicated to creating the smart laboratory of the future, has announced a collaboration with the Wellcome Sanger Institute that could lead to the faster development of drugs for diseases of the immune system like rheumatoid arthritis.
£3.9m project to support elimination of the world’s leading infectious cause of blindness
Stronger-SAFE is a £3.9m Wellcome Trust funded project that will increase our understanding of how trachoma is transmitted, and hopefully lead to the development and testing of new, more effective interventions and treatment approaches. Professor Nick Thomson, from the Wellcome Trust Sanger Institute and the London School of Hygiene & Tropical Medicine (LSHTM), is part of the team that are using new DNA sequencing approaches to better understand how this disease is spread.
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Rapid HIV disease progression following superinfection in an HLA-B*27:05/B*57:01-positive transmission recipient.
Mapping the malaria parasite druggable genome by using in vitro evolution and chemogenomics.
Science (New York, N.Y.) 2018;359;6372;191-199
Antimicrobial resistant Klebsiella pneumoniae carriage and infection in specialized geriatric care wards linked to acquisition in the referring hospital.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2018
Designing an intuitive web application for drug discovery scientists.
Drug discovery today 2018
Dairy Consumption and Body Mass Index Among Adults: Mendelian Randomization Analysis of 184802 Individuals from 25 Studies.
Clinical chemistry 2018;64;1;183-191
Single-cell RNA-sequencing resolves self-antigen expression during mTEC development.
Scientific reports 2018;8;1;685
Terminal Pleistocene Alaskan genome reveals first founding population of Native Americans.
miR-96 is required for normal development of the auditory hindbrain.
Human molecular genetics 2018
Making new genetic diagnoses with old data: iterative reanalysis and reporting from genome-wide data in 1,133 families with developmental disorders.
Genetics in medicine : official journal of the American College of Medical Genetics 2018
Deconvolution of multiple infections in Plasmodium falciparum from high throughput sequencing data.
Bioinformatics (Oxford, England) 2018;34;1;9-15