Archive Page: Hubbard Group | Vertebrate Genome Analysis

Archive Page: Hubbard Group | Vertebrate Genome Analysis

Archive Page: Hubbard Group

This archive page is being maintained as a historical record of the research of the Vertebrate Genome Analysis group under the leadership of Professor Tim Hubbard and is no longer being updated

Our Research and Approach

Please note: This page is no longer being updated and was last edited in 2013.

Genome sequences provide a natural index for organising and understanding biological data.

Following the sequencing of the human and other vertebrate genomes, vertebrate genome browsers such as Ensembl have become critical resources, providing biologists with integrated access to the sequence and its associated annotation. The activities of the Vertebrate genome analysis team revolve around generating and presenting core vertebrate genome annotation, particularly in the form of reference genesets, and in maintaining the reference genome sequences of human, mouse and zebrafish. As well as contributing to resources used globally, the team is involved in a wide variety of collaborations related to genome annotation and the development of improved methods for analysis and annotation resulting in many publications. Tim Hubbard was the principal investigator of the team until he left the Sanger Institute in 2013 to become Professor of Bioinformatics, Head of Department of Medical and Molecular Genetics at King's College London and overall Director of Bioinformatics for King's Health Partners/King's College London.

Read More

Publications

  • Petabyte-scale innovations at the European Nucleotide Archive.

    Cochrane G, Akhtar R, Bonfield J, Bower L, Demiralp F et al.

    Nucleic acids research 2009;37;Database issue;D19-25

  • Ensembl 2009.

    Hubbard TJ, Aken BL, Ayling S, Ballester B, Beal K et al.

    Nucleic acids research 2009;37;Database issue;D690-7

  • The Protein Feature Ontology: a tool for the unification of protein feature annotations.

    Reeves GA, Eilbeck K, Magrane M, O'Donovan C, Montecchi-Palazzi L et al.

    Bioinformatics (Oxford, England) 2008;24;23;2767-72

  • BioJava: an open-source framework for bioinformatics.

    Holland RC, Down TA, Pocock M, Prlić A, Huen D et al.

    Bioinformatics (Oxford, England) 2008;24;18;2096-7

  • Integrating biological data--the Distributed Annotation System.

    Jenkinson AM, Albrecht M, Birney E, Blankenburg H, Down T et al.

    BMC bioinformatics 2008;9 Suppl 8;S3