The Genome Reference Informatics Team analyses genome assemblies to reveal and correct quality issues and to identify and add variation. The team consists of Senior Bioinformaticians and Senior Computer Biologists to cover software development, data analysis and genome curation. Besides comissioning sequencing and generation of other genome data (e.g. optical mapping), we develop bespoke software like gEVAL to identify and visualize genome assembly issues. This is used by our curators to resolve those issues through changes or additions to the assemblies. We are also creating de novo assemblies for individuals/strains.
Our team represents the Sanger Institute within the Genome Reference Consortium, and we work closely with our consortium partners and other collaborators to ensure access to the latest data and analyses. Assembly improvements are submitted to INSDC on a regular schedule.