Genome Refernce Infomatics

Sanger Institute, Genome Research Limited

Key Projects, Collaborations, Tools & Data

The Genome Reference Informatics Team is responsible for the reference genome assemblies of human, mouse and zebrafish. We are also involved in the analysis and improvement of assemblies of 16 mouse strains, chicken, individual humans and additional zebrafish strains.  

Partners and Funders

External Partners and Funders


  • gEVAL - a web-based browser for evaluating genome assemblies.

    Chow W, Brugger K, Caccamo M, Sealy I, Torrance J and Howe K

    Bioinformatics (Oxford, England) 2016;32;16;2508-10

  • Using optical mapping data for the improvement of vertebrate genome assemblies.

    Howe K and Wood JM

    GigaScience 2015;4;10

  • The zebrafish reference genome sequence and its relationship to the human genome.

    Howe K, Clark MD, Torroja CF, Torrance J, Berthelot C et al.

    Nature 2013;496;7446;498-503

  • Modernizing reference genome assemblies.

    Church DM, Schneider VA, Graves T, Auger K, Cunningham F et al.

    PLoS biology 2011;9;7;e1001091