The genomics of gene regulation group is interested in understanding the role of gene regulatory variation in human disease and evolution.
Headed by Daniel Gaffney, the group combines computational and statistical methods with high-throughput experimental techniques to understand the role played by changes in gene regulation in disease susceptibility and human evolution. We are currently involved in both the data generation and analysis of molecular phenotypes in human induced pluripotent stem cells as part of the Human Induced Pluripotent Stem Cells Initiative
The team aims to understand how genetic changes affect the level, location and timing of gene expression using a combination of experimental and computational methods. We are particularly focussed on understanding this variation in pluripotent stem cells as a model of human disease and development.
We welcome applications from prospective postdocs and PhD students. Projects are available in the areas of genomics of gene regulation, molecular evolution and on population genomics of gene regulation. All our work involves data analysis, but there is also scope for projects with a component of laboratory work. Interested applicants should send a CV to Dan (see profile page for contact details), with information on your research, publications and contact details for three references.
For more information, please click "Read more" below.