Mouse Genomes Project
The ability to manipulate the mouse genome, together with the wealth of disease models, inbred strains and genomic resources, makes the mouse the premier model organism for genetic approaches to mammalian biology. Over a century of mouse genetics has provided scores of inbred strains, spontaneous and engineered mutations, making the mouse unsurpassed as a model system for investigating human disease. Access to complete sequence of multiple inbred strains will add to these resources and will become a permanent foundation for a systems biology approach to phenotypic variation in the mouse.
The Mouse Genomes Project uses next generation sequencing technologies to sequence the genomes of key laboratory mouse strains. We are releasing the raw sequence data, SNPs, short indels, structural variants, assembled chromosomes, and strains specific gene annotation under our data release policy.
|129P2/OlaHsd View||129S1/SvImJ View||129S5SvEvBrd View||A/J View|
|AKR/J View||BALB/cJ View||BTBR View||BUB/BnJ View|
|C3H/HeH View||C3H/HeJ View||C57BL/10J View||C57BL/6NJ View|
|C57BR/cdJ View||C57L/J View||C58/J View||CAST/EiJ View|
|CBA/J View||DBA/1J View||DBA/2J View||FVB/NJ View|
|I/LnJ View||KK/HiJ View||LEWES/EiJ View||LP/J View|
|MOLF/EiJ View||NOD/ShiLtJ View||NZB/B1NJ View||NZO/HlLtJ View|
|NZW/LacJ View||PWK/PhJ View||RF/J View||SEA/GnJ View|
|SPRET/EiJ View||ST/bJ View||WSB/EiJ View||ZALENDE/EiJ View|
The sample accession codes are listed here.
Mouse genomic variation and its effect on phenotypes and gene regulation.
Next-generation sequencing of experimental mouse strains.
Mammalian genome : official journal of the International Mammalian Genome Society 2012;23;9-10;490-8
The fine-scale architecture of structural variants in 17 mouse genomes.
Genome biology 2012;13;3;R18
The genomic landscape shaped by selection on transposable elements across 18 mouse strains.
Genome biology 2012;13;6;R45
High levels of RNA-editing site conservation amongst 15 laboratory mouse strains.
Genome biology 2012;13;4;26
Sequencing and characterization of the FVB/NJ mouse genome.
Genome biology 2012;13;8;R72
Sequence-based characterization of structural variation in the mouse genome.
This sequencing centre plans on publishing the completed and annotated sequences in a peer-reviewed journal as soon as possible. Permission of the principal investigator should be obtained before publishing analyses of the sequence/open reading frames/genes on a chromosome or genome scale. See our data sharing policy.
Data Release Policy
The Mouse Genomes Project releases sequence data, SNPs and other variant calls as a service to the research community. These data are released in accordance with the Fort Lauderdale agreement and Toronto agreements. As producers of these data we reserve the right to be the first to publish a genome-wide analysis of the data we have generated. The pre-publication data that we release via this website is embargoed for publication except for analyses of single chromosomes in single strains or single gene loci across multiple strains. We strongly encourage researchers to contact us if there are any queries about referencing or publishing analysis based on pre-publication data obtained via this website. More information on the Wellcome Trust Sanger Institute's data sharing policy.
If you have a query about using the project data in your studies or publications, we are happy to answer any queries and can be contacted at firstname.lastname@example.org
For any queries about the data produced by the project or how to use the data, we can be contacted at: email@example.com