GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
A5PLF0_DANRE IFI44 ENSDARG00000010729 None Not determined 1
A5PLF0_DANRE IFI44L ENSDARG00000010729 None Not determined 1
A9JTH3_DANRE PPP2R2B ENSDARG00000044334 None Not determined 2
ANK3 (2 of 2) ANK3 ENSDARG00000061736 10 Not determined 6
anks1b ANKS1B ENSDARG00000003512 5 Not determined 7
ANO5 (2 of 2) ANO5 ENSDARG00000015731 2 Not determined 1
ano5b ANO5 ENSDARG00000036147 1 Not determined 1
as3mt AS3MT ENSDARG00000027572 None Not determined 3
cacna1c CACNA1C ENSDARG00000008398 4 1 phenotype 7
CACNA1C CACNA1C ENSDARG00000037904 None Not determined 7
cacnb2a CACNB2 ENSDARG00000079906 None Not determined 8
cacnb2b CACNB2 ENSDARG00000055565 2 Not determined 8
cnnm2a CNNM2 ENSDARG00000061195 2 Not determined 9
cnnm2b CNNM2 ENSDARG00000078733 2 Not determined 9
CSMD1 CSMD1 ENSDARG00000058353 1 Not determined 12
dcp1b DCP1B ENSDARG00000045484 None Not determined 3
dpyd DPYD ENSDARG00000010267 1 Not determined 3
DPYD (4 of 5) DPYD ENSDARG00000086853 None Not determined 3
DPYD (3 of 5) DPYD ENSDARG00000086464 None Not determined 3
DPYD (2 of 5) DPYD ENSDARG00000089675 1 Not determined 3
E2J8V4_DANRE TCF4 ENSDARG00000087652 None Not determined 9
eno1 ENO1 ENSDARG00000022456 1 Not determined 1
fam155a FAM155A ENSDARG00000075858 1 Not determined 4
FAM155A (1 of 2) FAM155A ENSDARG00000086224 None Not determined 4
grik1a GRIK1 ENSDARG00000069139 2 Not determined 6
grin2aa GRIN2A ENSDARG00000034493 3 Not determined 3
grin2ab GRIN2A ENSDARG00000070543 2 Not determined 3
hdac4 HDAC4 ENSDARG00000041204 3 Not determined 4
itm1 STT3A ENSDARG00000053832 4 Not determined 2
kif5c KIF5C ENSDARG00000076027 4 Not determined 1
LOC100332699 HDAC4 ENSDARG00000089416 1 Not determined 4
LOC100332780 ZMIZ1 ENSDARG00000076477 2 Not determined 10
LOC100334523 NTRK3 ENSDARG00000063035 None Not determined 2
LOC559645 SLC35F2 ENSDARG00000090686 2 Not determined 1
LOC561540 GRIK1 ENSDARG00000040627 3 Not determined 6
LOC564761 ITIH3 ENSDARG00000055053 5 Not determined 4
LOC799658 IFI44 ENSDARG00000056501 None Not determined 1
LOC799658 IFI44L ENSDARG00000056501 None Not determined 1
lypd6b LYPD6B ENSDARG00000077643 None Not determined 1
MAP4K4 MAP4K4 ENSDARG00000093661 None Not determined 1
MMP16 (3 of 3) MMP16 ENSDARG00000025111 None Not determined 4
mmp16a MMP16 ENSDARG00000088118 None Not determined 4
mmp16b MMP16 ENSDARG00000058876 2 Not determined 4
nt5c2a NT5C2 ENSDARG00000039399 3 Not determined 9
nt5c2b NT5C2 ENSDARG00000058231 2 Not determined 9
ntrk3b NTRK3 ENSDARG00000077228 2 Not determined 2
odz4 ODZ4 ENSDARG00000034264 5 Not determined 4
PPP2R2B (2 of 3) PPP2R2B ENSDARG00000053673 None Not determined 2
ppp2r2bb PPP2R2B ENSDARG00000079583 None Not determined 2
Q5RHP7_DANRE SYNE1 ENSDARG00000009499 18 2 normal 5
rerea RERE ENSDARG00000077353 7 Not determined 4
rereb RERE ENSDARG00000075670 4 Not determined 4
sema3aa SEMA3A ENSDARG00000019235 5 Not determined 5
sema3ab SEMA3A ENSDARG00000042210 3 Not determined 5
sema3h SEMA3A ENSDARG00000042616 3 Not determined 5
si:ch211-197g15.10 IFI44L ENSDARG00000071361 None Not determined 1
si:ch211-197g15.10 IFI44 ENSDARG00000071361 None Not determined 1
si:ch211-197g15.5 IFI44L ENSDARG00000009673 2 Not determined 1
si:ch211-197g15.5 IFI44 ENSDARG00000009673 2 Not determined 1
si:ch211-197g15.6 IFI44L ENSDARG00000094747 1 Not determined 1
si:ch211-197g15.6 IFI44 ENSDARG00000094747 1 Not determined 1
si:ch211-197g15.7 IFI44 ENSDARG00000071355 3 Not determined 1
si:ch211-197g15.7 IFI44L ENSDARG00000071355 3 Not determined 1
si:ch211-197g15.8 IFI44 ENSDARG00000094984 None Not determined 1
si:ch211-197g15.8 IFI44L ENSDARG00000094984 None Not determined 1
si:ch211-197g15.9 IFI44 ENSDARG00000002293 2 Not determined 1
si:ch211-197g15.9 IFI44L ENSDARG00000002293 2 Not determined 1
si:dkey-193b15.5 IFI44 ENSDARG00000092883 1 Not determined 1
si:dkey-193b15.5 IFI44L ENSDARG00000092883 1 Not determined 1
si:dkey-226m8.10 SMARCA2 ENSDARG00000060578 None Not determined 1
si:dkey-79f11.10 IFI44L ENSDARG00000093857 None Not determined 1
si:dkey-79f11.10 IFI44 ENSDARG00000093857 None Not determined 1
si:dkey-79f11.4 IFI44 ENSDARG00000007602 None Not determined 1
si:dkey-79f11.4 IFI44L ENSDARG00000007602 None Not determined 1
si:dkey-79f11.5 IFI44L ENSDARG00000075791 None Not determined 1
si:dkey-79f11.5 IFI44 ENSDARG00000075791 None Not determined 1
si:dkey-79f11.7 IFI44 ENSDARG00000092361 None Not determined 1
si:dkey-79f11.7 IFI44L ENSDARG00000092361 None Not determined 1
si:dkey-79f11.8 IFI44L ENSDARG00000095673 None Not determined 1
si:dkey-79f11.8 IFI44 ENSDARG00000095673 None Not determined 1
si:dkeyp-122e7.1 ZNF804A ENSDARG00000027079 4 Not determined 3
si:dkeyp-75b4.9 IFI44 ENSDARG00000015678 None Not determined 1
si:dkeyp-75b4.9 IFI44L ENSDARG00000015678 None Not determined 1
si:dkeyp-9d4.2 IFI44 ENSDARG00000029720 None Not determined 1
si:dkeyp-9d4.2 IFI44L ENSDARG00000029720 None Not determined 1
slc17a6a SLC17A6 ENSDARG00000001127 4 Not determined 1
slc17a6b SLC17A6 ENSDARG00000041150 1 Not determined 1
slc35f2 SLC35F2 ENSDARG00000069745 None Not determined 1
smarca2 SMARCA2 ENSDARG00000008904 3 Not determined 1
SYNE1 (1 of 2) SYNE1 ENSDARG00000063068 22 Not determined 5
TCF4 (1 of 2) TCF4 ENSDARG00000075546 1 Not determined 9
zfpm2a ZFPM2 ENSDARG00000040123 None Not determined 5
zfpm2b ZFPM2 ENSDARG00000035997 1 Not determined 5
zgc:110377 ITIH3 ENSDARG00000055036 1 Not determined 4
zgc:153372 AS3MT ENSDARG00000068967 2 Not determined 3
zgc:153505 DPYD ENSDARG00000071482 None Not determined 3
zgc:153654 IFI44L ENSDARG00000060322 2 Not determined 1
zgc:153654 IFI44 ENSDARG00000060322 2 Not determined 1
zgc:158635 SLC45A1 ENSDARG00000004302 2 Not determined 2
zgc:171763 ANK3 ENSDARG00000077582 6 Not determined 6
zgc:63629 ELTD1 ENSDARG00000013653 None Not determined 2
zgc:73056 ENO1 ENSDARG00000013750 None Not determined 1
zmiz1 ZMIZ1 ENSDARG00000074502 8 Not determined 10

The following reported genes could not be linked automatically to a zebrafish gene:

  • BANK1
  • CCDC68
  • IL1R2
  • MGC16025
  • MHC region
  • MHC region
  • MIR137
  • PCGEM1
  • RAB39
* quick link - http://q.sanger.ac.uk/uipna9v3