GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

GWAS of dental caries patterns in the permanent dentition.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
abcg2a ABCG2 ENSDARG00000043037 None Not determined 10
abcg2b ABCG2 ENSDARG00000079361 None Not determined 10
abcg2c ABCG2 ENSDARG00000058574 3 Not determined 10
abcg2d ABCG2 ENSDARG00000016818 1 Not determined 10
ATXN7L1 ATXN7L1 ENSDARG00000089860 1 Not determined 3
ednra EDNRA ENSDARG00000011876 6 Not determined 4
exoc2 EXOC2 ENSDARG00000055610 None Not determined 5
ift88 IFT88 ENSDARG00000027234 3 Not determined 2
LOC559590 NFASC ENSDARG00000056910 1 Not determined 1
LOC792710 BCORL1 ENSDARG00000077912 1 Not determined 1
lyz LYZL2 ENSDARG00000057789 None Not determined 1
lzts2 LZTS1 ENSDARG00000074597 None Not determined 3
myo16 MYO16 ENSDARG00000078582 1 Not determined 5
nfasca NFASC ENSDARG00000061099 3 Not determined 1
nkx2.3 NKX2-3 ENSDARG00000039095 1 Not determined 10
nkx2.7 NKX2-3 ENSDARG00000021232 1 1 phenotype 10
nr4a3 NR4A3 ENSDARG00000055854 1 Normal 1
pcdh9 PCDH9 ENSDARG00000063264 None Not determined 3
pkd2 PKD2 ENSDARG00000014098 2 Not determined 1
prom1a PROM1 ENSDARG00000039966 5 Not determined 2
prom1b PROM1 ENSDARG00000034007 1 Not determined 2
scpp1 DSPP ENSDARG00000090416 None Not determined 1
si:ch211-119o8.6 ZNF98 ENSDARG00000026972 1 Not determined 3
si:ch211-215c3.2 ZNF827 ENSDARG00000076171 6 Not determined 4
si:dkey-11c8.1 AJAP1 ENSDARG00000038655 None Not determined 1
si:dkey-121j17.1 NT5DC1 ENSDARG00000006797 2 Not determined 1
si:dkey-63d15.13 LZTS1 ENSDARG00000075565 1 Not determined 3
smad7 SMAD7 ENSDARG00000016858 None Not determined 7
spsb1 SPSB1 ENSDARG00000056515 None Not determined 3
spsb4b SPSB1 ENSDARG00000040538 2 Not determined 3
stm DMP1 ENSDARG00000035694 1 Not determined 1
tgfbr1a TGFBR1 ENSDARG00000017494 None Not determined 1
tgfbr1b TGFBR1 ENSDARG00000042259 None Not determined 1
trib2 TRIB2 ENSDARG00000068179 2 Not determined 2
twsg1a TWSG1 ENSDARG00000033428 None Not determined 1
twsg1b TWSG1 ENSDARG00000074831 None Not determined 1
wsb1 WSB1 ENSDARG00000021343 None Not determined 2
wu:fj90d02 LZTS1 ENSDARG00000077207 None Not determined 3
zgc:136367 ACAD9 ENSDARG00000055620 2 Not determined 1
zgc:85942 EDNRA ENSDARG00000062262 1 Not determined 4
zgc:92022 PHTF2 ENSDARG00000077204 None Not determined 3
znf516 ZNF516 ENSDARG00000070809 3 Not determined 3

The following reported genes could not be linked automatically to a zebrafish gene:

  • CTNNA3
  • IBSP
  • LPAR3
  • LPPR5
  • MEPE
  • SFTA1P
  • SPP1
* quick link - http://q.sanger.ac.uk/w0m07bhj