GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Genetic variants associated with breast size also influence breast cancer risk.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
A5PN56_DANRE AREG ENSDARG00000076853 None Not determined 1
A5PN56_DANRE AREGB ENSDARG00000076853 None Not determined 1
A9JTG6_DANRE CADPS ENSDARG00000070567 1 Not determined 2
adoa ADO ENSDARG00000042827 1 Not determined 4
adob ADO ENSDARG00000053571 None Not determined 4
atp2b4 ATP2B4 ENSDARG00000044902 3 Not determined 3
B0S746_DANRE TTN ENSDARG00000000563 54 1 phenotype, 1 normal 2
B3DIN8_DANRE SEC14L2 ENSDARG00000074570 1 Not determined 1
ca16b PTPRG ENSDARG00000060123 3 Not determined 5
CADPS (1 of 2) CADPS ENSDARG00000043661 3 Not determined 2
ccnd1 CCND1 ENSDARG00000035750 2 Not determined 2
chek2 CHEK2 ENSDARG00000025820 1 Not determined 4
comtd1 COMTD1 ENSDARG00000078918 2 Not determined 1
epb41l5 EPB41L5 ENSDARG00000032324 3 Not determined 1
esr1 ESR1 ENSDARG00000004111 None Not determined 14
gap43 GAP43 ENSDARG00000015775 None Not determined 1
gli2a GLI2 ENSDARG00000025641 8 Not determined 3
gli2b GLI2 ENSDARG00000020884 3 Not determined 3
GPC6 (4 of 4) GPC6 ENSDARG00000090456 None Not determined 9
GPC6 (3 of 4) GPC6 ENSDARG00000036468 2 Not determined 9
GPC6 (2 of 4) GPC6 ENSDARG00000086960 None Not determined 9
im:7162084 CCND1 ENSDARG00000019741 None Not determined 2
inhbb INHBB ENSDARG00000040777 1 Not determined 4
KIRREL3 (2 of 3) KIRREL3 ENSDARG00000086919 None Not determined 4
kirrel3a KIRREL3 ENSDARG00000075806 1 Not determined 4
kirrel3l KIRREL3 ENSDARG00000019473 None Not determined 4
LOC100005846 ELMO1 ENSDARG00000055400 None Not determined 8
LOC100333044 GCKR ENSDARG00000086620 None Not determined 39
LOC100333111 ZNF703 ENSDARG00000067720 None Not determined 1
LOC572369 KIRREL3 ENSDARG00000060939 3 Not determined 4
LOC797480 MKL1 ENSDARG00000075867 4 Not determined 3
LOC799320 ZNF365 ENSDARG00000087985 None Not determined 11
MTFP1 MTFP1 ENSDARG00000032111 1 Not determined 1
nedd1 NEDD1 ENSDARG00000013472 1 Not determined 1
NP_001036789.1 PTHLH ENSDARG00000071070 None Not determined 1
NP_001036789.1 PTHLH ENSDARG00000088586 None Not determined 1
NP_998256.1 ELMO1 ENSDARG00000019258 3 Not determined 8
pabpc1l RBMS3 ENSDARG00000002597 2 Not determined 3
pthlh PTHLH ENSDARG00000031737 None Not determined 1
ptprga PTPRG ENSDARG00000045006 4 Not determined 5
rbms3 RBMS3 ENSDARG00000044574 1 Not determined 3
si:ch211-106i3.6 FAM48A ENSDARG00000078658 1 Not determined 1
si:ch211-137a8.2 CLMN ENSDARG00000068926 3 Normal 4
si:ch211-193c2.2 FAM109B ENSDARG00000067546 None Not determined 1
si:ch211-89f7.1 SEC14L2 ENSDARG00000059729 1 Not determined 1
si:dkey-237i9.1 SEC14L2 ENSDARG00000070336 None Not determined 1
slc4a1ap SLC4A1AP ENSDARG00000034160 2 Not determined 2
tbc1d22a TBC1D22A ENSDARG00000045510 1 Not determined 2
tlr3 TLR3 ENSDARG00000016065 None Not determined 1
TMCC1 (2 of 2) TMCC1 ENSDARG00000076747 None Not determined 1
ttna TTN ENSDARG00000028213 59 2 phenotypes 2
ttnb TTN ENSDARG00000091908 14 1 phenotype 2
wbp2 WBP2NL ENSDARG00000044852 None Not determined 1
wu:fb39e12 MKL1 ENSDARG00000076229 2 Not determined 3
zgc:100997 CLMN ENSDARG00000043667 1 Not determined 4
zgc:103502 CCND1 ENSDARG00000027391 None Not determined 2
zgc:114196 TFAP2D ENSDARG00000023272 2 Not determined 1
zgc:123333 NAGA ENSDARG00000020742 3 Not determined 1
zgc:153733 FAM109B ENSDARG00000053257 None Not determined 1
zgc:153972 TMCC1 ENSDARG00000060954 3 Not determined 1
zgc:158867 C6orf97 ENSDARG00000016161 1 Not determined 8
zgc:171629 GPC6 ENSDARG00000091739 None Not determined 9
zgc:77174 TDRD3 ENSDARG00000025421 1 Not determined 2
znf277 ZNF277 ENSDARG00000025346 1 Not determined 1
znf703 ZNF703 ENSDARG00000035563 1 Not determined 1

The following reported genes could not be linked automatically to a zebrafish gene:

  • ALDH7A1P4
  • DEFB112
  • EPGN
  • EREG
  • FLJ43860
  • IFITM9P
  • LOC100128607
  • LOC100128818
  • LOC100129646
  • LOC642846
  • LOC645207
  • LOC646513
  • LOC728715
  • LOC84931
  • MESTP4
  • MIR135A2
  • MRPS7P1
  • NOL4
  • NPCDR1
  • NUFIP1P
  • RPL19P8
  • RPL23AP37
  • SDC4P
  • SERPINA6
  • SPA17P1
* quick link - http://q.sanger.ac.uk/ct13bmvl